616281
L-Glutamic acid-2,3,3,4,4-d5
97 atom % D, 98% (CP)
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About This Item
Linear Formula:
HO2C(CD2)2CD(NH2)CO2H
Molecular Weight:
152.16
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Product Name
L-Glutamic acid-2,3,3,4,4-d5, 97 atom % D, 98% (CP)
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i1D2,2D2,3D
SMILES string
[2H]C([2H])(C(O)=O)C([2H])([2H])[C@]([2H])(N)C(O)=O
InChI key
WHUUTDBJXJRKMK-NKXUJHECSA-N
isotopic purity
97 atom % D
assay
98% (CP)
form
solid
optical activity
[α]25/D +31°, c = 2 in 5 M HCl
mp
205 °C (dec.) (lit.)
mass shift
M+5
Quality Level
Related Categories
Biochem/physiol Actions
Glutamic acid (or glutamate) functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as gamma-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase.
Appl- L-Glutamic acid-2,3,3,4,4-d5 has been used as an internal standard in metabolomics and lipidomics profiling.
Appl- L-Glutamic acid-2,3,3,4,4-d5 has been used as an internal standard in metabolomics and lipidomics profiling.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.
DeBerardinis RJ
Cell Metabolism, 7(1), 11-20 (2008)
Glutamic Acid, Twenty Years Later
S. Garattini
The Journal of Nutrition, 130(4), 901S-909S (2000)
Flavia Bianchi et al.
Insects, 11(11) (2020-11-22)
The production of phagostimulant and attractive volatile organic compounds (VOCs) by yeasts can be exploited to improve the efficacy of attract-and-kill formulations against the spotted wing drosophila (SWD). This study evaluated the persistence over one week of a yeast-based formulation
Metabolomics and lipidomics using traveling-wave ion mobility mass spectrometry.
Paglia G and Astarita G
Nature Protocols, 12(4), 797-797 (2017)
Amino acids: metabolism, functions, and nutrition.
Wu G
Amino Acids, 37(1), 1-17 (2009)
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