732613
Poly(ethylene glycol) methyl ether
average MN 20,000, methoxy, hydroxyl
Synonym(s):
Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
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About This Item
Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene glycol) methyl ether, average Mn 20,000
SMILES string
O(CCO)C
InChI
1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
InChI key
XNWFRZJHXBZDAG-UHFFFAOYSA-N
vapor density
>1 (vs air)
vapor pressure
0.05 mmHg ( 20 °C)
form
powder or crystals
mol wt
average Mn 20,000
mp
64-69 °C
Mw/Mn
≤1.2
Ω-end
hydroxyl
α-end
methoxy
storage temp.
−20°C
Quality Level
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Related Categories
Application
- Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C.: This study develops PEGylated chitosan micelles grafted with deoxycholic acid for effective delivery of mitomycin C, showcasing the potential of PEGylated compounds in pharmaceutical formulations and drug delivery systems (Zhang et al., 2015).
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
359.6 °F
flash_point_c
182 °C
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Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
Hyo Won Seo et al.
Biomaterials, 34(11), 2748-2757 (2013-01-25)
The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. To increase the efficacy and reduce the toxicity of systemically administered
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
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