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Merck

81300

Poly(ethylene glycol)

greener alternative

average MN 20,000, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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Product Name

Poly(ethylene glycol), average Mn 20,000

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

form

flakes

mol wt

average Mn 20,000

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

63-66 °C

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

Quality Level

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Application

PEG has been used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.

Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Other Notes

Molecular weight: Mn 16,000-24,000

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Xu Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14330-14337 (2012-09-20)
Understanding the interface between DNA and nanomaterials is crucial for rational design and optimization of biosensors and drug delivery systems. For detection and delivery into cells, where high concentrations of cellular proteins are present, another layer of complexity is added.
Carrie F Olson-Manning
Molecular biology and evolution, 37(8), 2257-2267 (2020-03-21)
Metabolic networks are complex cellular systems dependent on the interactions among, and regulation of, the enzymes in the network. Although there is great diversity of types of enzymes that make up metabolic networks, the models meant to understand the possible
Chien-Chi Lin et al.
Biomaterials, 32(36), 9685-9695 (2011-09-20)
Hydrogels provide three-dimensional frameworks with tissue-like elasticity and high permeability for culturing therapeutically relevant cells or tissues. While recent research efforts have created diverse macromer chemistry to form hydrogels, the mechanisms of hydrogel polymerization for in situ cell encapsulation remain
Teagan E Bate et al.
Soft matter, 15(25), 5006-5016 (2019-06-06)
Self-organization of kinesin-driven, microtubule-based 3D active fluids relies on the collective dynamics of single microtubules. However, the connection between macroscopic fluid flows and microscopic motion of microtubules remains unclear. In this work, the motion of single microtubules was characterized by
Oliver J Harrison et al.
Cell reports, 30(8), 2655-2671 (2020-02-27)
Non-clustered δ1- and δ2-protocadherins, close relatives of clustered protocadherins, function in cell adhesion and motility and play essential roles in neural patterning. To understand the molecular interactions underlying these functions, we used solution biophysics to characterize binding of δ1- and

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