A10809
4′-Hydroxy-3′-methoxyacetophenone
98%
Synonym(s):
Acetovanillone, Apocynin
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About This Item
Linear Formula:
HOC6H3(OCH3)COCH3
CAS Number:
Molecular Weight:
166.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-854-5
Beilstein/REAXYS Number:
637373
MDL number:
Assay:
98%
Form:
powder
InChI
1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI key
DFYRUELUNQRZTB-UHFFFAOYSA-N
SMILES string
COc1cc(ccc1O)C(C)=O
assay
98%
form
powder
bp
263-265 °C/17 mmHg (lit.)
Quality Level
mp
112-115 °C (lit.)
Related Categories
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Jingfei Zhang et al.
Neuron, 82(1), 195-207 (2014-03-19)
Complement receptor 3 (CR3) activation in microglia is involved in neuroinflammation-related brain disorders and pruning of neuronal synapses. Hypoxia, often observed together with neuroinflammation in brain trauma, stroke, and neurodegenerative diseases, is thought to exacerbate inflammatory responses and synergistically enhance brain
Elham Khanicheh et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2187-2192 (2013-08-03)
Antioxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an nicotinamide adenine dinucleotide phosphate oxidase inhibitor with anti-inflammatory properties. We used contrast-enhanced ultrasound molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative
Ji Chen et al.
Hypertension (Dallas, Tex. : 1979), 61(3), 681-689 (2012-12-26)
Angiotensin-converting enzyme 2 (ACE2) is a lately discovered enzyme catalyzing Angiotensin II into Angiotensin 1-7. Angiotensin II has been reported to impair endothelial progenitor cell (EPC) function and is detrimental to stroke. Here, we studied the role of ACE2 in
Stephen J Kentish et al.
The Journal of physiology, 592(15), 3287-3301 (2014-06-01)
Neuronal nitric oxide (NO) plays an important role in gastric motor activity and modulates the mechanosensitivity of gastro-oesophageal vagal afferents. Effects of NO on food intake are dependent on feeding status. We sought to determine the effect of NO on
Julio Madrigal-Matute et al.
Journal of the American Heart Association, 3(4) (2014-08-07)
Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating
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