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Merck

P27100

N-Phenylmaleimide

97%

Synonym(s):

1-Phenyl-pyrrole-2,5-dione, 1-[4-(Acetoxy)phenyl]maleimide

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About This Item

Empirical Formula (Hill Notation):
C10H7NO2
CAS Number:
Molecular Weight:
173.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-382-0
Beilstein/REAXYS Number:
125098
MDL number:

Product Name

N-Phenylmaleimide, 97%

assay

97%

form

solid

InChI key

HIDBROSJWZYGSZ-UHFFFAOYSA-N

InChI

1S/C10H7NO2/c12-9-6-7-10(13)11(9)8-4-2-1-3-5-8/h1-7H

SMILES string

O=C1C=CC(=O)N1c2ccccc2

bp

162-163 °C/12 mmHg (lit.)

mp

85-87 °C (lit.)

Quality Level

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Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Michael L Vasil et al.
Antimicrobial agents and chemotherapy, 56(12), 6223-6234 (2012-09-26)
The twin-arginine translocase (TAT) in some bacterial pathogens, including Pseudomonas aeruginosa, Burkholderia pseudomallei, and Mycobacterium tuberculosis, contributes to pathogenesis by translocating extracellular virulence determinants across the inner membrane into the periplasm, thereby allowing access to the Xcp (type II) secretory
Yan Wang et al.
The Journal of organic chemistry, 77(8), 4143-4147 (2012-04-05)
A Me-DuPhos-catalyzed efficient asymmetric [3 + 2] cycloaddition reaction between Morita-Baylis-Hillman carbonates of isatins and N-phenylmaleimide has been developed. This reaction constructs three chiral centers in one step to afford spirocyclopentaneoxindoles in good yields (up to 84%) with excellent diastereo-
I Velasco-Guillén et al.
Archives of biochemistry and biophysics, 372(1), 121-127 (1999-11-24)
The Ca(2+)-ATPase from sarcoplasmic reticulum reacts with phenylmaleimide, producing the inhibition of the ATPase activity following a pseudo-first-order kinetic with a rate constant of 19 M(-1) s(-1). Calcium and ATP binding are not altered upon phenylmaleimide inhibition. However, the presence
S Xu et al.
Biophysical journal, 82(4), 2111-2122 (2002-03-28)
It is well established that in a skeletal muscle under relaxing conditions, cross-bridges exist in a mixture of four weak binding states in equilibrium (A*M*ATP, A*M*ADP*P(i), M*ATP, and M*ADP*P(i)). It has been shown that these four weak binding states are
Au(I)-catalyzed enantioselective 1,3-dipolar cycloadditions of münchnones with electron-deficient alkenes.
Asa D Melhado et al.
Journal of the American Chemical Society, 129(42), 12638-12639 (2007-09-29)

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