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R1757

D-(−)-Ribose

Name: <SC>D</SC>-(−)-Ribose
Brand: ALDRICH

98%

Synonym(s):

D-Ribose

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About This Item

Empirical Formula (Hill Notation):

C₅H₁₀O₅

CAS Number:

50-69-1

Molecular Weight:

150.13

UNSPSC Code:

12352201

NACRES:

NA.22

PubChem Substance ID:

24899349

EC Number:

200-059-4

Beilstein/REAXYS Number:

1723081

MDL number:

MFCD00135453

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Properties

Quality Level

100

assay

98%

optical activity

[α]20/D −19.7°, c = 4 in H₂O

mp

88-92 °C (lit.)

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure.

Carine Baraguey et al.

Organic & biomolecular chemistry, 11(16), 2638-2647 (2013-03-05)

The pivaloyloxymethyl (PivOM) group is a biolabile 2'-O-ribose protection that is under development in a prodrug-based approach for siRNA applications. Besides an expected cellular uptake, nucleic acid sequences carrying PivOM showed also increased nuclease resistance and, in most cases, an

Translating the concept of peptide labeling with 5-deoxy-5-[18F]fluororibose into preclinical practice: 18F-labeling of Siglec-9 peptide for PET imaging of inflammation.

Xiang-Guo Li et al.

Chemical communications (Cambridge, England), 49(35), 3682-3684 (2013-03-29)

Peptide glycosylation with 5-deoxy-5-[(18)F]fluororibose was translated into preclinical settings. The novel (18)F-labeled Siglec-9 peptide was produced using an automated synthesis procedure. The (18)F-labeled Siglec-9 peptide showed favorable binding in the animal model of inflammation in vivo.

Poly(A)-specific ribonuclease (PARN): an allosterically regulated, processive and mRNA cap-interacting deadenylase.

Anders Virtanen et al.

Critical reviews in biochemistry and molecular biology, 48(2), 192-209 (2013-03-19)

Deadenylation of eukaryotic mRNA is a mechanism critical for mRNA function by influencing mRNA turnover and efficiency of protein synthesis. Here, we review poly(A)-specific ribonuclease (PARN), which is one of the biochemically best characterized deadenylases. PARN is unique among the

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