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Merck

444212

MMP-2 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10⁵ M⁻¹s⁻¹).

Synonym(s):

MMP-2 Substrate, Fluorogenic

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About This Item

Empirical Formula (Hill Notation):
C49H68N14O15
Molecular Weight:
1093.15
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
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Quality Level

assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

color

yellow

solubility

DMSO: 10 mg/mL

fluorescence

λex ~325 nm, λem ~393 nm

shipped in

ambient

storage temp.

−20°C

General description

A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 105 M-1s-1; excitation maximum: ~325 nm; emission maximum: ~393 nm).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A quenched fluorescence substrate for MMP-2 (gelatinase A)
Product does not compete with ATP.
Reversible: no

Other Notes

MCA-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂[Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]
Murphy, G., et al. 1994. J. Biol. Chem. 269, 6632.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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