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Merck

ABN14

Anti-Brain lipid binding protein Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Brain lipid-binding protein, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, brain lipid binding protein, fatty acid binding protein 7, brain, mammary-derived growth inhibitor-related

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Brain lipid binding protein Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

packaging

antibody small pack of 25 μg

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

ambient

target post-translational modification

unmodified

Quality Level

Gene Information

human ... FABP7(2173)
mouse ... Fabp7(12140)

Application

Detect Brain lipid binding protein using this Anti-Brain lipid binding protein Antibody validated for use in WB, IH.
Immunohistochemistry Analysis: A 1:300 dilution of ABN14 antibody from a previous lot detected Brain lipid binding protein in mouse cerebellum tissue.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Analysis Note

Control
P1 mouse brain tissue lysate
Evaluated by Western Blot in P1 mouse brain tissue lysate.

Western Blot Analysis: 0.01 µg/ml of this antibody detected Brain lipid-binding protein in 10 µg of P1 mouse brain tissue lysate.

Biochem/physiol Actions

Rat homology - 88%.
This antibody recognizes Brain lipid-binding protein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

BLBP (Brain lipid-binding protein) belongs to a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBPs play essential roles in fatty acid uptake, transport and metabolism. BLBP can be used as a molecular marker for radial glia (a major neural progenitor cell type and a scaffolding supporting neuronal migration) in the developing central nervous system. Radial glia play an essential role in the generation of the cerebral cortex through their function as neuronal precursors and as neuronal migration guides.
~ 15 kDa

Immunogen

Epitope: Cytoplasmic Domain
GST-tagged recombinant protein corresponding to human Brain lipid-binding protein.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB9558

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vivek K Bajpai et al.
Stem cells (Dayton, Ohio), 35(5), 1402-1415 (2017-02-01)
During development, neural crest (NC) cells are induced by signaling events at the neural plate border of all vertebrate embryos. Initially arising within the central nervous system, NC cells subsequently undergo an epithelial to mesenchymal transition to migrate into the
Mayumi Okamoto et al.
Nature communications, 7, 11349-11349 (2016-04-21)
During cerebral development, many types of neurons are sequentially generated by self-renewing progenitor cells called apical progenitors (APs). Temporal changes in AP identity are thought to be responsible for neuronal diversity; however, the mechanisms underlying such changes remain largely unknown.
Chrysoula Konstantinidou et al.
BMC biology, 14(1), 94-94 (2016-10-26)
In vertebrate organisms, the neural crest (NC) gives rise to multipotential and highly migratory progenitors which are distributed throughout the embryo and generate, among other structures, the peripheral nervous system, including the intrinsic neuroglial networks of the gut, i.e. the
Yanyan Sun et al.
Cell death & disease, 8(5), e2781-e2781 (2017-05-12)
Mitochondria contribute to neonatal hypoxic-ischemic brain injury by releasing potentially toxic proteins into the cytosol. CHCHD4 is a mitochondrial intermembrane space protein that plays a major role in the import of intermembrane proteins and physically interacts with apoptosis-inducing factor (AIF).
Shane Stegeman et al.
PloS one, 8(7), e68287-e68287 (2013-07-19)
The deubiquitylating enzyme Usp9x is highly expressed in the developing mouse brain, and increased Usp9x expression enhances the self-renewal of neural progenitors in vitro. USP9X is a candidate gene for human neurodevelopmental disorders, including lissencephaly, epilepsy and X-linked intellectual disability.

Global Trade Item Number

SKUGTIN
ABN1404053252277825
ABN14-25UG04054839342608

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