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Merck

CCYTOMAG-90K

MILLIPLEX® Canine Cytokine/Chemokine Panel

Configurable Canine Cytokine/Chemokine 13-Plex Panel

Synonym(s):

canine interleukin immunoassay panel, luminex canine cytokine chemokine growth factor multiplex assay, luminex canine pro inflammatory anti inflammatory cytokine panel, millipore canine inflammation multiplex kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Canine Cytokine/Chemokine Panel, Configurable Canine Cytokine/Chemokine 13-Plex Panel

species reactivity

canine

manufacturer/tradename

Milliplex®

Quality Level

200

packaging

1 ea of

assay range

accuracy: 91-109%
sensitivity: 13.6 pg/mL
(IFN-γ)
sensitivity: 21.0 pg/mL
(MCP-1)
sensitivity: 21.7 pg/mL
(IL-8)
sensitivity: 3.2 pg/mL
(IP-10)
sensitivity: 3.5 pg/mL
(IL-2)
sensitivity: 3.7 pg/mL
(IL-6)
sensitivity: 5.3 pg/mL
(KC-like)
sensitivity: 5.8 pg/mL
(IL-18)
sensitivity: 6.1 pg/mL
(TNFα)
sensitivity: 7.5 pg/mL
(IL-7)
sensitivity: 8.5 pg/mL
(IL-10)
sensitivity: 9.0 pg/mL
(IL-15)
sensitivity: 9.2 pg/mL
(GM-CSF)
standard curve range: 12.2-50,000 pg/mL
(All analytes)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
There was no or negligible cross-reactivity among different analytes within the panel.

Preparation Note

Recommended storage for kit components is 2 - 8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

  • Comprehensive 13-plex panel: Simultaneously quantifies essential inflammatory markers across multiple canine sample types including serum, plasma, cell culture supernatants, and tissue lysates.
  • High-throughput efficiency with sample conservation: 96-well format processes up to 38 samples in duplicate while requiring only 25 μL per test, maximizing productivity while preserving valuable biological specimens for additional analyses.
  • Advanced canine health and disease research: Investigate immune responses in breed-specific disorders, age-related conditions, vaccine efficacy studies, and nutritional immunology research to improve veterinary care and canine welfare outcomes.
  • Flexible protocol options: Choose between overnight 4°C incubation for convenience or 2-hour room temperature protocol for same-day results, accommodating diverse laboratory workflows and experimental timelines.

General description

In addition to studying inflammation for dog nutrition and disease research, canine animal models are important for human biomedical research and drug development. Cytokine and chemokines are molecular mediators of immune cell response in inflammation and immunity. Quantification of cytokines and chemokines is essential to understanding the immune system, as well as for researching disease states such as autoimmune, allergic reactions, sepsis, and cancer.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 13 analytes in canine serum, plasma, and cell culture supernatants.

Analytes included: GM-CSF, IFNγ, IP-10, IL-2, IL-6, IL-7, IL-8, IL-10, IL-15, IL-18, KC-like, MCP-1, TNF-α

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Herman Borghys et al.
Journal of Alzheimer's disease : JAD, 56(2), 763-774 (2016-12-31)
Understanding differences in Alzheimer's disease biomarkers before the pathology becomes evident can contribute to an improved understanding of disease pathogenesis and treatment. A decrease in amyloid-β (Aβ)42 in cerebrospinal fluid (CSF) is suggested to be a biomarker for Aβ deposition
Pia Martiny et al.
Frontiers in veterinary science, 6, 208-208 (2019-07-19)
Septic peritonitis (SP) is common in dogs and is associated with high mortality. Early recognition is essential to maximizing survival and may be aided by biomarker measurement. The present study aimed to evaluate the ability of biomarkers to discriminate septic
Teresa Cejalvo et al.
Cancer research, 78(17), 4891-4901 (2018-07-12)
Dogs with spontaneous tumors treated in veterinary hospitals offer an excellent opportunity for studying immunotherapies, including oncolytic viruses. Oncolytic viruses have advanced into the clinic as an intratumorally administered therapeutic; however, intravenous delivery has been hindered by neutralization in the
Anna Brunner et al.
Frontiers in veterinary science, 8, 652479-652479 (2021-07-06)
Background: The degree of systemic inflammation, reperfusion injury and endothelial activation are potentially important determinants of clinical outcomes in dogs with gastric dilatation volvulus (GDV). Objective: To evaluate plasma concentrations and kinetics of inflammatory markers in dogs with GDV over
Robert Goggs et al.
Veterinary record open, 7(1), e000366-e000366 (2020-08-22)
Platelet transfusion is indicated for haemorrhage due to severe thrombocytopenia and for trauma associated coagulopathy. Febrile non-haemolytic transfusion reactions are a common complication of platelet transfusions in people and may be due to accumulated inflammatory cytokines. The present study aimed
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Global Trade Item Number

SKUGTIN
CCYTOMAG-90K-0304053252801228
CCYTOMAG-90K-0604053252801259
CCYTOMAG-90K-0904053252801280
CCYTOMAG-90K-11C04055977106312
CCYTOMAG-90K-1204053252801310
CCYTOMAG-90K-03C04055977108101
CCYTOMAG-90K-13C04055977099041
CCYTOMAG-90K-1004053252801297
CCYTOMAG-90K-04C04055977098976
CCYTOMAG-90K-0404053252801235
CCYTOMAG-90K-0104053252801204
CCYTOMAG-90K-02C04055977106299
CCYTOMAG-90K-01C04055977098969
CCYTOMAG-90K-0204053252801211
CCYTOMAG-90K-05C04055977098983
CCYTOMAG-90K-10C04055977099027
CCYTOMAG-90K-06C04055977106305
CCYTOMAG-90K-1304053252801327
CCYTOMAG-90K-0804053252801273
CCYTOMAG-90K-08C04055977099003
CCYTOMAG-90K-1104053252801303
CCYTOMAG-90K-12C04055977099034
CCYTOMAG-90K-0704053252801266
CCYTOMAG-90K-09C04055977099010

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