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Merck

30-1940

Thiourea

JIS special grade, ≥98.0%

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
PubChem Substance ID:
UNSPSC Code:
12352300
Beilstein/REAXYS Number:
605327
MDL number:
Assay:
≥98.0%
Form:
solid
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grade

JIS special grade

assay

≥98.0%

form

solid

availability

available only in Japan

mp

170-176 °C (lit.)

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins


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signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Yoshiji Takemoto
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Ai-Fang Li et al.
Chemical Society reviews, 39(10), 3729-3745 (2010-08-26)
This critical review highlights recent advances in the structurally modified (thio)urea-based receptors for anion complexation and sensing. Modifications of the (thio)urea structure are aimed at a better anion binding in terms of higher binding constant, anion selectivity and feasibility. Major
Iris Keren et al.
Science (New York, N.Y.), 339(6124), 1213-1216 (2013-03-09)
Bactericidal antibiotics kill by modulating their respective targets. This traditional view has been challenged by studies that propose an alternative, unified mechanism of killing, whereby toxic reactive oxygen species (ROS) are produced in the presence of antibiotics. We found no