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Merck

46289

Furaltadone

VETRANAL®, analytical standard

Synonym(s):

5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O6
CAS Number:
139-91-3
Molecular Weight:
324.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757123
EC Number:
205-384-5
Beilstein/REAXYS Number:
8130725
MDL number:
MFCD00057356

Product Name

Furaltadone, VETRANAL®, analytical standard

InChI key

YVQVOQKFMFRVGR-VGOFMYFVSA-N

InChI

1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CC(CN3CCOCC3)OC2=O)o1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

Quality Level

200

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Furaltadone may be used as an analytical reference standard for the quantification of the analyte in milk samples and poultry eggs using different chromatography techniques.

General description

Furaltadone is a nitrofuran drug, with broad-spectrum antimicrobial activity. It is widely used in veterinary medicine for intensive animal production, especially in pigs, poultry, fish and to provide resistance against infections caused by Escherichia coli and Salmonella.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3647
BCCD2702
BCCB0543

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Determination of nitrofurantoin, furazolidone and furaltadone in milk by high-performance liquid chromatography with electrochemical detection
Diaz G.T, et al.
Analytical Methods : Advancing Methods and Applications, 764(2), 243-248 (1997)
Sara Leston et al.
Chemosphere, 82(7), 1010-1016 (2010-11-27)
The use of pharmaceuticals in the food production industry as prophylatic and therapeutic agents is necessary to promote animal health, but may entail significant consequences to natural ecosystems, especially in the cases of overdosing and use of banned pharmaceuticals. The
L P Jager et al.
European journal of pharmacology, 331(2-3), 325-331 (1997-07-23)
Changes in the biogenesis of corticosteroids caused by nitrofurans were studied. The three nitrofurans used: furazolidone, furaltadone and nitrofurantoin, altered the steroid production/release by porcine adrenocortical cells in vitro during 1 h incubations. With pregnenolone as a substrate the nitrofurans
M C Mahedero et al.
Journal of pharmaceutical and biomedical analysis, 29(3), 477-485 (2002-06-14)
An UV spectroscopic method is proposed to analyze mixtures of the nitrofuran derivatives, nitrofurantoin, furaltadone and furazolidone, used in veterinary. The change of absorption spectra due to photo-decomposition is used. A 20% dimethylformamide/water, basic medium of pH 9.4 (ammonium chloride/ammonia)
Zhen-Lin Xu et al.
Talanta, 103, 306-313 (2012-12-04)
A heterologous competitive indirect enzyme-linked immunosorbent assay (ciELISA) for the determination of the furaltadone metabolite 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ) was developed. AMOZ was derivatised with 2-(4-formylphenoxy) acetic acid or 2-(3-formylphenoxy) acetic acid to obtain two novel immunizing haptens. The ability of these
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