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Merck

72210

Neutral Red

suitable for microscopy

Synonym(s):

3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5, Toluylene red

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About This Item

Empirical Formula (Hill Notation):
C15H17ClN4
CAS Number:
Molecular Weight:
288.78
EC Number:
209-035-8
UNSPSC Code:
12171500
NACRES:
MA.02
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3918740
Colour Index Number:
50040
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form

powder or crystals

Quality Level

technique(s)

titration: suitable

pH

6.8-8.0, red to yellow

mp

290 °C (dec.) (lit.)

solubility

water: 0.01 g/10 mL

εmax

≥800 at 535-545 nm

suitability

suitable for microscopy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1

InChI

1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H

InChI key

PGSADBUBUOPOJS-UHFFFAOYSA-N

General description

Neutral red is a vital dye widely used as a cellular pH indicator and is selective for shifts in pH. It is highly lipophilic in nature. It favours membrane potential dependent fluorescence that attributes to changes in hydrophobicity.

Application

Neutral red has been used to stain mouse mammary glands.
Useful as an indicator for preparing neutral red paper, and as a biological stain.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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John D Landua et al.
Journal of mammary gland biology and neoplasia, 14(4), 411-415 (2009-11-26)
Whole mount preparations of mouse mammary glands are useful for evaluating overall changes in growth and morphology, and are essential for detecting and evaluating focal or regionally-localized phenotypes that would be difficult to detect or analyze using other techniques. We
Sylvie V M Tesson et al.
Frontiers in microbiology, 9, 2681-2681 (2018-11-30)
Microalgae are common members of the atmospheric microbial assemblages. Diverse airborne microorganisms are known to produce ice nucleation active (INA) compounds, which catalyze cloud and rain formation, and thus alter cloud properties and their own deposition patterns. While the role
Gennady A Evtugyn et al.
Talanta, 102, 156-163 (2012-11-28)
New aptasensors based on DNA aptamer and polycarboxylated thiacalix[4]arenes in cone, 1,3-alternate and partial cone configurations bearing Neutral Red (NR) at substituents at the lower rim have been developed and applied for thrombin detection. The assembly of the biorecognition layer