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M8640

1-Methoxy-5-methylphenazinium methyl sulfate

≥95% purity , powder

Synonym(s):

1-Methoxyphenazine methosulfate

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About This Item

Empirical Formula (Hill Notation):
C15H16N2O5S
CAS Number:
65162-13-2
Molecular Weight:
336.36
NACRES:
NA.47
PubChem Substance ID:
329818065
UNSPSC Code:
12171500
EC Number:
265-579-6
MDL number:
MFCD00040648
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Product Name

1-Methoxy-5-methylphenazinium methyl sulfate, ≥95%

Quality Level

200

assay

≥95%

form

powder

composition

Nitrogen: ≥ 7.9%

technique(s)

titration: suitable

color

red to brown

solubility

H2O: 1 mg/mL, clear, red

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

COS([O-])(=O)=O.COc1cccc2[n+](C)c3ccccc3nc12

InChI

1S/C14H13N2O.CH4O4S/c1-16-11-7-4-3-6-10(11)15-14-12(16)8-5-9-13(14)17-2;1-5-6(2,3)4/h3-9H,1-2H3;1H3,(H,2,3,4)/q+1;/p-1

InChI key

MASUWVVNWALEEM-UHFFFAOYSA-M

General description

1-Methoxy-5-methylphenazinium methyl sulfate (MPMS) is a photochemically stable electron-transport mediator between NAD(P)H and tetrazolium dyes. The reduced form of MPMS converts tetrazolium salt to purple precipitate formazan.It is a very stable and non-enzymic electron carrier that mediates electron transfer by dehydrogenases in vitro to various electron acceptors such as tetrazolium dyes or the electrode of an enzymic electric cell.

Application

1-Methoxy-5-methylphenazinium methyl sulfate has been used as a component of buffers or solutions for the assay of lactate dehydrogenase and muscle succinate dehydrogenase.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2

target_organs

Nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB0197
MKCZ8159
MKCM0974
MKCL6166
MKCL2964

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Patries M Herst et al.
Biochimica et biophysica acta, 1767(2), 170-177 (2007-02-03)
Oxygen consumption for bioenergetic purposes has long been thought to be the prerogative of mitochondria. Nevertheless, mitochondrial gene knockout (rho(0)) cells that are defective in mitochondrial respiration require oxygen for growth and consume oxygen at the cell surface via trans-plasma
Kuniyo Inouye et al.
Journal of biochemistry, 131(1), 97-105 (2002-01-05)
A synchronous enzyme-reaction system using water-soluble formazan and a non-enzymatic electron mediator was developed and applied to an enzyme immunoassay (EIA). The reaction system consists of four steps: (I) dephosphorylation of NADP(+) to produce NAD(+) by alkaline phosphatase (ALP), (II)
An optimized lactate dehydrogenase release assay for screening of drug candidates in neuroscience.
Kaja S, et. al.
Journal of Pharmacological and Toxicological Methods, 73, 1-1 (2015)
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