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Merck

157953

Sodium hydrosulfite

technical grade

Synonym(s):

Sodium hypodisulfite

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About This Item

Linear Formula:
NaO2SSO2Na
CAS Number:
Molecular Weight:
174.11
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-890-0
MDL number:
Assay:
≥82.5% (iodometric)
Grade:
technical grade
Form:
powder
Solubility:
water: soluble(lit.)
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grade

technical grade

Quality Level

assay

≥82.5% (iodometric)

form

powder

pH

7-9 (20 °C, 50 g/L)

solubility

water: soluble(lit.)

cation traces

heavy metals: ≤0.002%

storage temp.

room temp

SMILES string

[Na+].[Na+].[O-]S(=O)S([O-])=O

InChI

1S/2Na.H2O4S2/c;;1-5(2)6(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2

InChI key

JVBXVOWTABLYPX-UHFFFAOYSA-L

General description

Sodium hydrosulfite (Sodium dithionite, Sodium hypodisulfite, Na2S2O4) is a white crystalline sodium salt. It decomposes in the presence of atmospheric oxygen to afford sodium hydrogen sulfate. It has been prepared by reducing sodium hydrogen sulfite in sulfurous acid solution with zinc. It is widely used for the decolorization prior to dyeing of cloths in the textile industry.

Application

Sodium hydrosulfite may be employed as a reducing agent for the reduction of graphite oxide in a study.
Sodium hydrosulfite has been used as a fluorescent quenching agent in the encapsulation of polynucleotides via production of asymmetric nanoparticles. It has also be used in the form of buffer for the elution of probe labelled proteins involved in the indentification of cellular targets of covalent kinase inhibitors via mass spectrometry method (MS).


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Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Self-heat. 1

supp_hazards

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



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Evaluation of asymmetric liposomal nanoparticles for encapsulation of polynucleotides
Whittenton J, et al.
Langmuir, 24(16), 8533-8540 (2008)
A chemoproteomic method for identifying cellular targets of covalent kinase inhibitors
Chen C-Y and Zhang C
Genes & Cancer, 7, 148-148 (2016)
E Gabriele Panarelli et al.
Physical chemistry chemical physics : PCCP, 22(17), 9487-9493 (2020-04-22)
We report on a novel approach to the study of rates and short-lived intermediates of (bio)chemical reactions that involve paramagnetic species. Temperature-cycle Electron Paramagnetic Resonance (EPR) concerns the repeated heating of a reaction mixture in the cavity of an EPR