31390
Dextran from Leuconostoc spp.
Mr ~70,000
Synonym(s):
DEXTRAN 70
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About This Item
Linear Formula:
(C6H10O5)n
CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
biological source
(Leuconostoc spp)
Quality Level
form
powder
mol wt
Mr ~70,000
loss
≤7% loss on drying
color
white
mp
483 °C ((901 °F ))
solubility
water: 0.75 g/5mL, clear
absorption
≤0.05 at 375 nm in H2O at 10%
storage temp.
room temp
SMILES string
O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
InChI key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
General description
Dextran is an extracellular bacterial polymer of D-glucopyranose. It primarily consists of α-(1→6) linkage in the main chain and a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages.
Application
Dextran from Leuconostoc spp. has been used:
- for the isolation of islets from pancreatic tissue by centrifugation
- as a component of Earle′s bicarbonate buffer for placental perfusion
- for the isolation of rat brain microvessels
Biochem/physiol Actions
Dextran is a, which is commercially used as a drug, particularly as a blood plasma volume expander. It is used as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex, a cross-linked dextran is broadly used for the separation and purification of protein. In the food industry, dextran found its use as a thickener for jam and ice cream. It inhibits the crystallization of sugar, thereby enhancing moisture retention. This helps in maintaining the flavor and appearance of various food items.
Other Notes
Enhances immunoprecipitation sensitivity
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
flash_point_f
Not applicable
flash_point_c
Not applicable
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Sin-Yu Yang et al.
Transplantation proceedings, 51(5), 1458-1462 (2019-06-04)
Subcutaneous pockets provide an extrahepatic transplant site for islet grafting to treat type 1 diabetes. However, a hypoxic environment may cause central necrosis to islets and lead to graft failure. Our previous studies focused on a pre-treated subcutaneous site with
M F Dumon et al.
Electrophoresis, 11(10), 846-851 (1990-10-01)
A modification of crossed immunoelectrophoresis for the analysis of plasma lipoproteins is described and is called polyacrylamide gel-crossed immunoelectrophoresis. The incorporation of albumin in the first-dimensional gel facilitates the transfer of the larger lipoproteins containing apolipoprotein B from the first-dimensional
Farwa Sarwat et al.
International journal of biological sciences, 4(6), 379-386 (2008-10-28)
On the basis of high enzyme activity a newly isolated strain of L. mesenteroides CMG713 was selected for dextran production. For maximum yield of dextran, effects of various parameters such as pH, temperature, sucrose concentration and incubation period were studied.