A6661
Albumin, dinitrophenyl
lyophilized powder
Synonym(s):
DNP-albumin human
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About This Item
Product Name
Albumin, dinitrophenyl, lyophilized powder
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
biological source
human
form
lyophilized powder
extent of labeling
30-40 mol DNP per mol albumin
technique(s)
RNA extraction: suitable
impurities
Infectious agents, tested
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ALB(213)
Analysis Note
Source material has tested negative for HIV and HBsAg
Application
Albumin, dinitrophenyl has been used to assess degranulation from rat mast cells by treatment of:
- bakkenolide B
- 4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1)
- mifepristone
Used for detection in immunological analyses. Can be used as an immunological challenge to activate basophils via the IgE receptor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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B Jabril-Cuenod et al.
The Journal of biological chemistry, 271(27), 16268-16272 (1996-07-05)
Antigen receptors on T- and B-cells activate Ras through a signaling pathway that results in the tyrosine phosphorylation of Shc and the formation of a complex of Shc with the Grb2 adaptor protein. The high affinity receptor for immunoglobulin E
Xuan Che et al.
International journal of medical sciences, 17(2), 224-233 (2020-02-11)
Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relieve dysmenorrhea still needs to be further investigated.
G J Heywood et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51(4), 176-181 (2002-06-13)
Nicorandil is a potassium channel opener and nitric oxide (NO) donor, and the hypothesis was tested that these modes of action may inhibit cellular degranulation and release of tumour necrosis factor-alpha (TNF-alpha). TNF-alpha and beta-hexosaminidase secretion were measured from rat
Carolin N Zorn et al.
Scientific reports, 8(1), 15467-15467 (2018-10-21)
Antigen (Ag)-mediated crosslinking of IgE-loaded high-affinity receptors for IgE (FcεRI) on mast cells (MCs) triggers activation of proinflammatory effector functions relevant for IgE-associated allergic disorders. The cytosolic tyrosine kinase BTK and the SH2-containing inositol-5'-phosphatase SHIP1 are central positive and negative
Julien Stackowicz et al.
The Journal of experimental medicine, 218(10) (2021-09-04)
Gain-of-function mutations in NLRP3 are responsible for a spectrum of autoinflammatory diseases collectively referred to as "cryopyrin-associated periodic syndromes" (CAPS). Treatment of CAPS patients with IL-1-targeted therapies is effective, confirming a central pathogenic role for IL-1β. However, the specific myeloid
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