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Merck

A7430

Azadirachtin

~95%

Synonym(s):

azadirachtin A

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About This Item

Empirical Formula (Hill Notation):
C35H44O16
CAS Number:
11141-17-6
Molecular Weight:
720.71
NACRES:
NA.28
PubChem Substance ID:
24891232
UNSPSC Code:
12352212
MDL number:
MFCD00083241

Key Documents

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Product Name

Azadirachtin, ~95%

InChI

1S/C35H44O16/c1-8-15(2)24(38)49-18-12-19(48-16(3)36)32(26(39)43-6)13-46-21-22(32)31(18)14-47-34(42,27(40)44-7)25(31)29(4,23(21)37)35-20-11-17(30(35,5)51-35)33(41)9-10-45-28(33)50-20/h8-10,17-23,25,28,37,41-42H,11-14H2,1-7H3/t17?,18-,19?,20?,21+,22+,23?,25?,28?,29?,30?,31?,32-,33?,34-,35?/m0/s1

SMILES string

[H]C1([H])C2OC3([H])OC=CC3(O)C1C4(C)OC24[C@@]5(C)[C@@H](O)[C@@H]6OC[C@]7([C@H](C[C@H](OC(=O)C(C)=CC)[C@]8(COC(O)([C@H]58)C(=O)OC)[C@@]67[H])OC(C)=O)C(=O)OC

InChI key

FTNJWQUOZFUQQJ-CFYAVYSVSA-N

assay

~95%

form

solid

application(s)

agriculture
environmental

storage temp.

−20°C

Quality Level

100

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Application

Azadirachtin has been used as a standard for high performance liquid chromatography (HPLC) and for quantification in suspension cultures of Azadirachta indica (A. Juss).

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H317,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2917
BCCL5654
BCCL4570
BCCJ7099
BCCH2475

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Benshui Shu et al.
Scientific reports, 7(1), 13231-13231 (2017-10-19)
As an important botanical pesticide, azadirachtin demonstrates broad insecticidal activity against many agricultural pests. The results of a previous study indicated the toxicity and apoptosis induction of azadirachtin in Spodoptera frugiperda Sf9 cells. However, the lack of genomic data has
Statistical media optimization for cell growth and azadirachtin production in Azadirachta indica (A. Juss) suspension cultures
Prakash G and Srivastava AK
Process Biochemistry (Oxford, United Kingdom), 40(12), 3795-3800 (2005)
Cecilia Stahl Vieira et al.
Developmental and comparative immunology, 114, 103864-103864 (2020-09-13)
Rhodnius prolixus is an insect vector of two flagellate parasites, Trypanosoma rangeli and Trypanosoma cruzi, the latter being the causative agent of Chagas disease in Latin America. The R. prolixus neuroendocrine system regulates the synthesis of the steroid hormone ecdysone
Torranis Ruttanaphan et al.
Insects, 11(10) (2020-10-15)
Spodoptera frugiperda, a highly polyphagous insect pest from America, has recently invaded and widely spread throughout Africa and Asia. Effective and environmentally safe tools are needed for successful pest management of this invasive species. Natural molecules extracted from plants offer
Jayakumar Jerobin et al.
Carbohydrate polymers, 90(4), 1750-1756 (2012-09-05)
Azadirachtin a biological compound found in neem have medicinal and pesticidal properties. The present work reports on the encapsulation of neem oil nanoemulsion using sodium alginate (Na-Alg) by cross linking with glutaraldehyde. Starch and polyethylene glycol (PEG) were used as
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Product Information Sheet - A7430

Product Information Sheet

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