D2625
Dansyl chloride
BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)
Synonym(s):
5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C12H12ClNO2S
CAS Number:
Molecular Weight:
269.75
UNSPSC Code:
12352101
NACRES:
NA.26
PubChem Substance ID:
EC Number:
210-092-6
Beilstein/REAXYS Number:
2217205
MDL number:
product line
BioReagent
Quality Level
assay
≥99% (HPLC)
form
powder and chunks
color
yellow to yellow-orange
mp
72-74 °C (lit.)
solubility
acetone: 20 mg/mL
suitability
suitable for amino acid labeling
storage temp.
2-8°C
SMILES string
CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
InChI
1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
InChI key
XPDXVDYUQZHFPV-UHFFFAOYSA-N
Application
Dansyl chloride has been used:
- as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)
- in the derivatization of plasma samples
- in the quantification of immobilized alkaline phosphatase
A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Biochem/physiol Actions
Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.
Still not finding the right product?
Explore all of our products under Dansyl chloride
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Simultaneous separation and quantitation of amino acids and polyamines of forest tree tissues and cell cultures within a single high-performance liquid chromatography run using dansyl derivatization
Minocha R and Long S
Journal of Chromatography A, 1035(1), 63-73 (2004)
Covalent protein immobilization on glass surfaces: Application to alkaline phosphatase
Taylor RH, et al.
Journal of Biotechnology, 118(3), 265-269 (2005)
Measuring the poise of thiol/disulfide couples in vivo
Jones DP and Liang Y
Free radical biology & medicine, 47(10), 1329-1338 (2009)