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Merck

N1514

Nervonic acid

≥99% (capillary GC)

Synonym(s):

cis-15-Tetracosenoic acid, Selacholeic acid

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About This Item

Linear Formula:
CH3(CH2)7CH=CH(CH2)13COOH (cis)
CAS Number:
506-37-6
Molecular Weight:
366.62
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24897496
MDL number:
MFCD00010507
Beilstein/REAXYS Number:
1728551

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Product Name

Nervonic acid, ≥99% (capillary GC)

InChI key

GWHCXVQVJPWHRF-KTKRTIGZSA-N

SMILES string

CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O

InChI

1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-

biological source

plant

assay

≥99% (capillary GC)

form

powder

mp

42-43 °C (lit.)

functional group

carboxylic acid

lipid type

unsaturated FAs

shipped in

ambient

storage temp.

−20°C

Quality Level

100

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Application

Nervonic acid has been used as a synthetic lipid supplement in vitro to study about effect of the developmental diet in Drosophila lifespan.

Biochem/physiol Actions

Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.

Packaging

Sealed ampule.

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV0166
MKCS7765
MKCR9631
MKCS0794
MKCR0461

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Developmental diet regulates Drosophila lifespan via lipid autotoxins
Stefana MI, et al.
Nature Communications, 8(1), 1384-1384 (2017)
Y Mizushina et al.
Journal of molecular biology, 304(3), 385-395 (2000-11-25)
Unsaturated long-chain fatty acids selectively bind to the DNA binding sites of DNA polymerase beta and DNA topoisomerase II, and inhibit their activities, although the amino acid sequences of these enzymes are markedly different from each other. Computer modeling analysis
Arja T Erkkilä et al.
The Journal of craniofacial surgery, 16(5), 764-769 (2005-09-30)
The fatty acid profiles of serum lipids were examined in 53 ten-year-old cleft children. The children presented with different cleft types (cleft lip, cleft lip and palate, isolated cleft palate and submucuous cleft palate) and were recruited from the Finnish
Aleix Sala-Vila et al.
The Journal of nutrition, 134(4), 868-873 (2004-03-31)
Supplementation of formulas for full-term infants with long-chain (LC) PUFA [arachidonic acid (AA) and docosahexaenoic acid (DHA)] at levels resembling human milk is recommended because they provide biochemical and functional benefits to the neonate. The objective of this work was
Martin Karlsson et al.
Obesity (Silver Spring, Md.), 14(11), 1931-1939 (2006-12-01)
Fatty acid (FA) composition has a role in adipogenesis. The objective was to study serum phospholipid (PL) FAs in adolescents and their relation to abdominal adipose tissue (AT) compartments and metabolic markers. Abdominal AT was measured by magnetic resonance imaging
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