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Merck

P9107

Anti-Potassium Channel Kv1.3 (Charybdotoxin-Sensitive Voltage-Dependent Potassium Channel, HLK3) antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD02097210
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, WB CL
Species reactivity:
rat, mouse, human
Citations:
1
Technique(s):
immunocytochemistry: 1:50 using cells permeabilized with 0.2% Triton X-100, western blot (chemiluminescent): 1:200
Uniprot accession no.:
P22001

Key Documents

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Quality Level

100

Gene Information

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, mouse, human

technique(s)

immunocytochemistry: 1:50 using cells permeabilized with 0.2% Triton X-100, western blot (chemiluminescent): 1:200

UniProt accession no.

P22001

storage temp.

−20°C

target post-translational modification

unmodified

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem/physiol Actions

Recognizes a full-length Kv1.3 protein. Does not cross-react with other potassium channel antigens.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

highly purified GST fusion protein from the C-terminal of human potassium channel Kv1.3. The protein corresponds to amino acids 471-523.

Preparation Note

Protein A purified.

Physical form

Lyophilized from phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKBS2466
031M1426
098K1362
017K1299
090K1320

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Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

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