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Merck

S0652

Sucrose octasulfate–aluminum complex

Synonym(s):

Sucralfate

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About This Item

CAS Number:
PubChem Substance ID:
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
259-018-4
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InChI key

JTZPPHUZZDKEOC-RBQAPOGLSA-A

InChI

1S/C11H20O35S8.16Al.40H2O/c12-47(13,14)36-1-3-4(41-49(18,19)20)5(42-50(21,22)23)6(43-51(24,25)26)9(38-3)39-11(2-37-48(15,16)17)8(45-53(30,31)32)7(44-52(27,28)29)10(40-11)46-54(33,34)35;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h3-10H,1-2H2,(H,12,13,14)(H,15,16,17)(H,18,19,20)(H,21,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35);;;;;;;;;;;;;;;;;40*1H2/q;16*+3;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-48/t3-,4-,5+,6-,7+,8+,9+,10-,11-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1......................................................../s1

SMILES string

O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.[O-]S(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS([O-])(=O)=O)O[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O

form

powder

impurities

<0.5% chloride content

color

white to almost white

storage temp.

2-8°C

Quality Level

Gene Information

human ... PGA5(5222)

Biochem/physiol Actions

An alkaline aluminum−sucrose complex which inhibits peptic hydrolysis and raises gastric pH.

Analysis Note

Minimum 30% sucrose octasulfate (HPLC)

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Mitsuhiro Fujishiro et al.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 25 Suppl 1, 86-93 (2013-02-02)
Gastric endoscopic submucosal dissection (ESD) causes artificial gastric ulcers and there is no consensus regarding the optimal perioperative management in terms of prevention of intra- or postoperative bleeding and promotion of healing. Traditionally, 8-week administration of proton pump inhibitors (PPI)
Waleed Alhazzani et al.
Polskie Archiwum Medycyny Wewnetrznej, 122(3), 107-114 (2012-02-23)
Critically ill patients are at risk of developing stress ulcers in the upper digestive tract. Multiple risk factors have been associated with the development of this condition, with variable risk of association. Decades of research have suggested the benefit of
V P Nelamangala Ramakrishnaiah et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 14(7), 876-882 (2012-02-24)
Chronic radiation proctitis with bleeding is a common problem encountered following radiotherapy for pelvic malignancy. Sucralfate-steroid enema and formalin dab are two common nonsurgical treatments. A randomized trial was conducted to compare the efficacy of these two methods. This was
Ricky W McCullough
Medical hypotheses, 80(3), 230-233 (2012-12-26)
Irritable bowel syndrome (IBS), non-erosive reflux disorder (NERD), and functional dyspepsia (FD) are best classified as immuno-neuronal disorders of the mucosa or functional mucosal syndromes (FMS). Each appears to be clinically reversible using high potency sucralfate (HPS). In FMS of
Can sucralfate be effective to protect on peritoneal membrane in patients receiving peritoneal dialysis treatment?
Erim Gulcan et al.
Medical hypotheses, 78(3), 415-415 (2012-01-10)

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