T0557
Sodium taurodeoxycholate hydrate
BioXtra, ≥97% (TLC)
Synonym(s):
2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
C26H44NO6SNa · xH2O
CAS Number:
Molecular Weight:
521.69 (anhydrous basis)
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3901204
description
anionic
Quality Level
product line
BioXtra
assay
≥97% (TLC)
mol wt
micellar avg mol wt 3100
aggregation number
6
impurities
≤0.002% Phosphorus (P), ≤0.1% Insoluble matter
CMC
1-4 mM (20-25°C)
solubility
H2O: 0.5 M, clear, colorless to faintly yellow
anion traces
chloride (Cl-): ≤0.5%, sulfate (SO42-): ≤0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.01%, Mg: ≤0.005%, NH4+: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%
General description
Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.
Application
Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.
Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.
Still not finding the right product?
Explore all of our products under Sodium taurodeoxycholate hydrate
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Emanuel Berger et al.
Biochemical and biophysical research communications, 409(4), 610-615 (2011-05-25)
Inflammatory bowel diseases (IBD) are chronically relapsing and immune-mediated disorders of the gastrointestinal tract. Endoplasmic reticulum (ER) stress mechanisms in the epithelium have been demonstrated to be implemented into the pathogenesis of intestinal inflammation. Chemical chaperones have been demonstrated to
Stefanie Mühlfeld et al.
Hepatology (Baltimore, Md.), 56(6), 2387-2397 (2012-07-19)
The sodium taurocholate cotransporting polypeptide (Ntcp) is the major bile salt uptake transporter at the sinusoidal membrane of hepatocytes. Short-term feedback regulation of Ntcp by primary bile salts has not yet been investigated in vivo. Subcellular localization of Ntcp was
Salma Alavi et al.
Cell, 181(7), 1533-1546 (2020-07-08)
The gut microbiome is the resident microbial community of the gastrointestinal tract. This community is highly diverse, but how microbial diversity confers resistance or susceptibility to intestinal pathogens is poorly understood. Using transplantation of human microbiomes into several animal models