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About This Item
EC Number:
231-153-3
UNSPSC Code:
23201100
product line
Carboxen®
form
powder
packaging
bottle of 10 g
technique(s)
LPLC: suitable
surface area
~400 m2/g
matrix
Carboxen® 564
matrix active group
carbon
particle size
20-45 mesh
pore size
~0.13 cm3/g mesoporosity, ~0.14 cm3/g macroporosity, ~0.24 cm3/g microporosity, ~6-9 Å pore diameter
density
~0.61 g/mL (free fall density)
separation technique
reversed phase
Quality Level
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Features and Benefits
Features and Benefits:
- Spherical
- Hard (ball pan hardness >98%)
- Stable up to 400°C
- High purity
- Easy to pack
- Stable over entire pH range
- Do not create backpressure
- High osmotic shock stability
- Tapered pore sizing (from macro- to meso- to micro-)
General description
Carboxens are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables. Tapered pores result in increased thermodynamic and kinetic properties for both adsorption and desorption. The Carboxens vary in the relative percentage of pore structures (micro, meso, and macro), surface area, and surface pH.
Other Notes
For more information, please visit: specialty Carbon Adsorbents
Legal Information
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
4.2 - Pyrophoric and self-heating hazardous materials
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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The effects of temperature and pressure on the performance of Carboxen/PDMS fibres during solid phase microextraction (SPME) of headspace volatiles from cooked and raw turkey breast.
Brunton NP, et al.
Flavour and Fragrance Journal, 16(4), 294-302 (2001)
RSC Chromatography Monographs
Pawliszyn J. et al.
Applications of Solid Phase Microextraction, 64-65 (1999)
S W Jenkins et al.
Environmental science and pollution research international, 2(4), 207-210 (1995-07-01)
A simple, rapid method for the extraction of N-nitrosodimethylamine (NDMA) from drinking and surface waters was developed using Ambersorb 572. Development of an alternative method to classical liquid-liquid extraction techniques was necessary to handle the workload presented by implementation of
B D Page et al.
Journal of chromatography. A, 873(1), 79-94 (2000-04-11)
The headspace solid-phase microextraction (HS-SPME) efficiencies from vegetable oil of the recently available Carboxen-poly(dimethylsiloxane) (PDMS) and divinylbenzene-Carboxen-PDMS fibres were found to be much greater than those of the PDMS fibre for a number of volatile contaminants. Using these Carboxen-based fibres
Dawn M Chapman et al.
Journal of agricultural and food chemistry, 52(17), 5431-5435 (2004-08-19)
A rapid and automated solid phase microextraction (SPME) stable isotope dilution gas chromatography/mass spectrometry (GC-MS) method for 2-methoxy-3-isobutylpyrazine (MIBP) quantification in red wine was developed. Wines with 30% (w/v) NaCl and 2-methoxy-(2)H(3)-3-isobutylpyrazine internal standard were sampled with a 2 cm
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