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Merck

320617

Ethyl 4-hydroxy-3-methoxycinnamate

98%

Synonym(s):

Ethyl ferulate

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2C2H5
CAS Number:
Molecular Weight:
222.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
223-745-5
MDL number:
Assay:
98%
Form:
solid
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Quality Level

assay

98%

form

solid

bp

164-166 °C/0.5 mmHg (lit.)

mp

63-65 °C (lit.)

functional group

ester

SMILES string

CCOC(=O)\C=C\c1ccc(O)c(OC)c1

InChI

1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+

InChI key

ATJVZXXHKSYELS-FNORWQNLSA-N

Related Categories

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Rukhsana Sultana et al.
Journal of neurochemistry, 92(4), 749-758 (2005-02-03)
Alzheimer's disease (AD) is neuropathologically characterized by depositions of extracellular amyloid and intracellular neurofibrillary tangles, associated with loss of neurons in the brain. Amyloid beta-peptide (Abeta) is the major component of senile plaques and is considered to have a causal
Aiping Zhang et al.
Planta, 229(5), 1099-1108 (2009-02-24)
Radical coupling reactions between ethyl ferulate (Et-FA), a simple model for feruloyl polysaccharides in planta, and coniferyl alcohol (CA), a monolignol, were studied in order to better understand the polymer cross-coupling interactions among polysaccharides and monolignols or lignin, mediated by
Marzia Perluigi et al.
Journal of neuroscience research, 84(2), 418-426 (2006-04-25)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of amyloid-beta peptide (Abeta), a peptide that as both oligomers and fibrils is believed to play a central role in the development and progress of AD by inducing oxidative
Giovanni Scapagnini et al.
Advances in experimental medicine and biology, 698, 27-35 (2010-01-01)
In recent years there has been a growing interest, supported by a large number of experimental and epidemiological studies, in the beneficial effects of some commonly used food-derived products in preventingvarious age-related pathologic conditions, ranging from cancer to neurodegenerative diseases.
Vittorio Calabrese et al.
Clinics in dermatology, 26(4), 358-363 (2008-08-12)
Skin is one of the main targets for reactive oxygen species; thus, reactive oxygen species-induced damage and protein and lipid modifications occur, and skin can undergo a wide array of diseases, from photosensitivity to cancer. In this study, human dermal

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