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Semicarbazide

Name: Semicarbazide
Brand: ALDRICH

6 wt. % (on silica gel)

Synonym(s):

Aminourea, Hydrazinecarboxamide, Isosemicarbazide

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About This Item

Linear Formula:

H₂NCONHNH₂

CAS Number:

57-56-7

Molecular Weight:

75.07

NACRES:

NA.22

PubChem Substance ID:

24862206

UNSPSC Code:

12352125

MDL number:

MFCD00042824

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Properties

form

powder

Quality Level

100

composition

, 6 wt. % (on silica gel)

SMILES string

NNC(N)=O

InChI

1S/CH5N3O/c2-1(5)4-3/h3H2,(H3,2,4,5)

InChI key

DUIOPKIIICUYRZ-UHFFFAOYSA-N

Description

Application

Antibacterial activity: Semicarbazide derivatives, specifically thiosemicarbazide, exhibit significant antibacterial properties influenced by substituent position. This underscores its application in pharmaceutical synthesis and microbial resistance studies (Janowska et al., 2024).
Solar cell performance: The application of semicarbazide hydrochloride in suppressing deep-level traps significantly improves the efficiency of tin-based perovskite solar cells, highlighting its potential in energy materials research (Jia et al., 2023).

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.

Palak J Trivedi et al.

Gut, 67(6), 1135-1145 (2017-04-22)

Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of IBD. This clinical association is linked pathologically to the recruitment of mucosal T cells to the liver, via vascular adhesion protein (VAP)-1-dependent enzyme activity. Our aim was to examine the

Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.

Sathya Narayanan Patmanathan et al.

Scientific reports, 6, 25650-25650 (2016-05-11)

Oral squamous cell carcinoma (OSCC) is a lethal disease with a 5-year mortality rate of around 50%. Molecular targeted therapies are not in routine use and novel therapeutic targets are required. Our previous microarray data indicated sphingosine 1-phosphate (S1P) metabolism

Stereochemistry and cofactor identity status of semicarbazide-sensitive amine oxidases.

M M Palcic et al.

Progress in brain research, 106, 41-47 (1995-01-01)

The relationship between the soluble copper topaquinone amine oxidases, the membrane bound semicarbazide-sensitive amine oxidases and lysyl oxidase remains unclear. The stereochemical course of substrate oxidation has been determined for each enzyme type and these studies suggest that SSAO and

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