436240
BRIJ® O20
average Mn ~1,150
Synonym(s):
Polyoxyethylene (20) oleyl ether
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About This Item
Linear Formula:
C18H35(OCH2CH2)nOH, n~20
CAS Number:
Molecular Weight:
1149.53
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
description
non-ionic
Quality Level
mol wt
average Mn ~1,150
technique(s)
cell culture | mammalian: suitable, protein quantification: suitable
mp
25-30 °C (lit.)
HLB
15
SMILES string
O(CCO)CCCCCCCC\C=C/CCCCCCCC
InChI
1S/C20H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h9-10,21H,2-8,11-20H2,1H3/b10-9-
InChI key
KWVPFECTOKLOBL-KTKRTIGZSA-N
General description
Brij® O20 is a non-ionic surfactant that has an 18 carbon tail with a single double bond and the head contains 20 ethylene oxide moieties. It is polyethoxylated fatty alcohol that is hydrophilic in nature.
Application
Brij® O20 has been used:
- as a detergent in medium A to prepare single detergent micelle aggregates
- along with phosphate buffer saline (PBS) solution as the receptor solution for terbinafine (TBF) for in vitro permeation studies of TBF-free base in porcine skin
- as a detergent to isolate detergent-resistant membranes from the mouse brain and to determine the distribution of major mammalian brain gangliosides, GM1, GD1a, GD1b and GT1b
Legal Information
Brij is a registered trademark of Croda International PLC
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
>464.0 °F - Equilibrium method
flash_point_c
> 240 °C - Equilibrium method
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Mixed Micellization of Polyoxyethylene (20) Oleyl Ether with Cetylpyridinium Chloride at the Air-Water Interface
Desai S and Bhagwat SS
Journal of Surfactants and Detergents, 19(6), 1169-1174 (2016)
Pulkit Khatri et al.
Journal of pharmaceutical sciences, 107(8), 2198-2207 (2018-04-08)
The study aims to elucidate the mechanism and the role of the molecular structure of surfactants and lipids in the formation of oil-in-water (o/w) self-emulsified nanoemulsions (SENs). The hypothesis is that the overall change of Gibb's free energy (ΔGf) during
Towards a new universal way to describe the required hydrophilic lipophilic balance of oils using the phase inversion temperature of C10E4/n-octane/water emulsions
Royer M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 536, 165-171 (2018)