113727
Norphenylephrine hydrochloride
98%
Sinónimos:
α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride
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Acerca de este artículo
Fórmula lineal:
HOC6H4CH(CH2NH2)OH · HCl
Número CAS:
Peso molecular:
189.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
225-323-6
MDL number:
Assay:
98%
Form:
solid
Servicio técnico
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Permítanos ayudarleQuality Level
assay
98%
form
solid
mp
162-164 °C (lit.)
functional group
amine, hydroxyl
SMILES string
Cl.NCC(O)c1cccc(O)c1
InChI
1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H
InChI key
OWMFSWZUAWKDRR-UHFFFAOYSA-N
Application
Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit.
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L Jørgensen et al.
Urologia internationalis, 46(2), 176-179 (1991-01-01)
To study the acute effect of norfenefrine, given orally in aqueous solution, on the urethral closure function, profilometry was performed before and after administration of placebo and increasing doses of norfenefrine in 6 females with genuine stress incontinence. A weak
J F Coulon et al.
Journal of neurochemistry, 52(5), 1418-1424 (1989-05-01)
Phenolamines, particularly octopamines, are of special importance in avoidance behavior. In the Roman low avoidance (RLA) strain, p-octopamine can induce locomotor behavioral activity that is normally observed in the Roman high avoidance (RHA) strain. For these reasons, the levels of
R B Raffa et al.
European journal of pharmacology, 169(2-3), 317-320 (1989-10-10)
Administration of p-octopamine by intracerebroventricular (i.c.v.) or intrathecal (i.t.) routes, but not orally, produced antinociception in the acetylcholine-induced abdominal constriction test (ED50 = 24.8 and 3.6 micrograms, respectively). Likewise, i.c.v. and i.t., but not peripheral (up to 200 mg/kg s.c.)