762040
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester
for Copper-free Click Chemistry
Sinónimos:
DBCO-sulfo-NHS ester, DBCO-sulfo-SE
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Fórmula empírica (notación de Hill):
C25H21N2NaO8S
Peso molecular:
532.50
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
Assay:
≥90.0 %
Form:
solid
Servicio técnico
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Permítanos ayudarleQuality Segment
assay
≥90.0 %
form
solid
reaction suitability
reaction type: click chemistry, reagent type: linker
bp
30 -100 °C
mp
240-260 °C
solubility
water: soluble at 20 °C
storage temp.
−20°C
SMILES string
O=C(CCCCC(ON(C(CC1S(=O)(O[Na])=O)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
InChI
1S/C25H22N2O8S.Na/c28-22(11-5-6-12-24(30)35-27-23(29)15-21(25(27)31)36(32,33)34)26-16-19-9-2-1-7-17(19)13-14-18-8-3-4-10-20(18)26;/h1-4,7-10,21H,5-6,11-12,15-16H2,(H,32,33,34);/q;+1/p-1
InChI key
QXKHPYSXPCJSPR-UHFFFAOYSA-M
Application
Dibenzocyclooctyne-sulfo-N-hydroxysuccinimidyl ester may be used for the covalent modification of nano-sized metal-organic frameworks (NMOFs) with nucleic acids via click chemistry during the synthesis stimuli-responsive DNA-gated NMOFs. These NMOFs can act as carriers of a fluorescent agent or anticancer drug, making them highly useful in targeted drug release system.
Water soluble succinimidyl ester/NHS functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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