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Merck

1.51907

LiChrospher® 100 RP-18 endcapped (5 µm) HPLC Columns

L x I.D. 125 mm x 2 mm Hibar® RT HPLC Column

Sinónimos:

TM=["LiChrospher"] C18 HPLC column

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UNSPSC Code:
41115700
NACRES:
SB.52
Particle size:
5 μm
Matrix active group:
C18 (RP18), C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
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Nombre del producto

LiChrospher® 100 RP-18 endcapped (5µm) Hibar® RT 125-2, suitable for HPLC

material

stainless steel column

Quality Segment

agency

suitable for USP L1

product line

LiChrospher®

feature

endcapped

packaging

1 ea of

extent of labeling

21.6% Carbon loading

parameter

400 bar pressure, 60 °C max. temp.

technique(s)

HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)

column L × I.D.

12.5 cm × 2 mm

surface area

350 m2/g

matrix

fully porous particle

matrix active group

C18 (RP18), C18 bonding phase

particle size

5 μm

pore size

100 Å pore size

operating pH range

2-7.5

separation technique

reversed phase, supercritical fluid (SFC)

storage temp.

no temp limit

General description

HPLC column

Application


  • Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry: This study effectively utilizes the Ascentis® Express F5, 2.7 μm HPLC column to analyze complex pharmaceutical mixtures and identify degradation products, demonstrating the column′s high-resolution capabilities and robust performance in pharmaceutical analysis (Özcan et al., 2023).

  • Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product: This research highlights the use of the Ascentis® Express F5 HPLC column in developing stability-indicating methods for the analysis of tasimelteon, underscoring its crucial role in ensuring the quality and safety of pharmaceuticals through advanced analytical techniques (Özcan et al., 2020).

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Hibar is a registered trademark of Merck KGaA, Darmstadt, Germany
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany


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