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370656

Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt

Name: Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt
Brand: MM

Important intracellular second messenger implicated in the action of nitric oxide in many cell types.

Sinónimos:

Guanosine 3′,5′-cyclic Monophosphate, Sodium Salt, Cyclic GMP, G-3,5-MP, cGMP, Na

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Fórmula empírica (notación de Hill):

C₁₀H₁₁N₅O₇P · Na

Número CAS:

40732-48-7

Peso molecular:

367.19

UNSPSC Code:

41106305

NACRES:

NA.77

MDL number:

MFCD00038424

Assay:

>98% (HPLC)

Form:

solid

Storage condition:

OK to freeze, desiccated (hygroscopic)

Servicio técnico

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Propiedades

Quality Segment

100

description

Merck USA index - 14, 2709

assay

>98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4nc(nc(c4nc3)[O-])N)CO1)O

InChI

1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

InChI key

KMPIYXNEROUNOG-GWTDSMLYSA-M

Descripción

General description

An important intracellular second messenger implicated in mediating the action of nitric oxide in many cell types. Found to activate protein kinase G. Suppresses apoptosis in rat ovarian follicles.

Important intracellular second messenger implicated in the action of nitric oxide in many cell types. Activates protein kinase G. Suppresses apoptosis in rat ovarian follicles.

Biochem/physiol Actions

Primary Target
Activates protein kinase G

Product does not compete with ATP.

Reversible: no

Cell permeable: no

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

Other Notes

Chun, S.Y., et al. 1995. Endocrinology136, 3120.
Kaupp, U.B., and Koch, K.W. 1992. Annu. Rev. Physiol.54, 153.
Goldberg, N.D., and Haddox, M.K. 1977. Annu. Rev. Biochem. 46, 823.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c