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Merck

RKTX2MAG-37K

MILLIPLEX® Rat Kidney Toxicity Panel

Configurable Rat Kidney Toxicity 6-Plex Panel

Sinónimos:

Rat renal function multiplex, kidney filtration markers in rats, rat kidney damage panel, rat nephrotoxicity detection panel, rat proteinuria biomarker assay

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000


Nombre del producto

MILLIPLEX® Rat Kidney Toxicity Panel,

species reactivity

rat

Quality Segment

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

urine

assay range

accuracy: 70-123%, standard curve range: 0.00-2 ng/mL
(EGF), standard curve range: 0.01-10 ng/mL
(Lipocalin-2/NGAL), standard curve range: 0.01-8 ng/mL
(Cystatin C), standard curve range: 0.48-350 ng/mL
(β2M), standard curve range: 1.37-1,000 ng/mL
(AGP), standard curve range: 10.97-8,000 ng/mL
(Albumin), inter-assay cv: <15%
intra-assay cv: <10%
(All other analytes), inter-assay cv: <20%
intra-assay cv: <15%
(AGP)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Albumin, AGP, and β-2-Microglobulin reflect glomerular integrity and proteinuria. Cystatin C is a marker of filtration efficiency, while NGAL and EGF indicate tubular injury and regeneration. Together, these biomarkers provide a comprehensive view of kidney function and toxicity in rat models.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in rat urine samples.

Analytes Included: α-1-Acid Glycoprotein (AGP), Albumin, β-2-Microglobulin, Cystatin C, EGF, NGAL/Lipocalin-2
Note: Albumin is in a competitive assay format.

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Multiplex detection of 6 renal biomarkers in one assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with rat urine samples
Benefits:

  • Conserves sample volume and reagents through multiplexing
  • Improves data quality and reproducibility with magnetic bead format
  • Enables early detection and monitoring of renal impairment

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.


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pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



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