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31679

Chlorpromazine hydrochloride

VETRANAL®, analytical standard

Sinónimos:

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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Fórmula empírica (notación de Hill):
C17H19ClN2S · HCl
Número CAS:
69-09-0
Peso molecular:
355.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753883
EC Number:
200-701-3
Beilstein/REAXYS Number:
3779989
MDL number:
MFCD00012654
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grade

analytical standard

Quality Segment

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

General description

Chlorpromazine hydrochloride (CPZ) is an antipsychotic drug which belongs to phenothiazine neuroleptic group. It is used in treating mental or personality disorders.

Application

CPZ may have been used as standard for the determination of antipsychotic drug at a glassy carbon electrode using chemometric methods, such as classical least squares (CLS), principal component regression (PCR) and partial least squares (PLS).
Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number

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