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Merck

43866

Salidroside

analytical standard

Sinónimos:

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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Fórmula empírica (notación de Hill):
C14H20O7
Número CAS:
10338-51-9
Peso molecular:
300.30
NACRES:
NA.24
PubChem Substance ID:
329756416
UNSPSC Code:
85151701
MDL number:
MFCD00210553

Documentos clave

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InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

grade

analytical standard

assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

Quality Level

100

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Categorías relacionadas

General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L(, which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step. It has been reported to be neuroprotective and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Hazard Classifications

Eye Irrit. 2

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCN2554
BCCM4309
BCCL2086
BCCH2071
BCCD9981

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Wieland Peschel et al.
Phytochemistry, 86, 92-102 (2012-11-10)
The demand for plant material of Rhodiola rosea L. (Crassulaceae) for medicinal use has increased recently, amid concerns about its quality and sustainability. We have analysed the content of phenylpropanoids (total rosavins) and salidroside in liquid extracts from 3-year old
A Panossian et al.
Phytotherapy research : PTR, 19(10), 819-838 (2005-11-02)
Plant adaptogens are compounds that increase the ability of an organism to adapt to environmental factors and to avoid damage from such factors. The beneficial effects of multi-dose administration of adaptogens are mainly associated with the hypothalamic-pituitary-adrenal (HPA) axis, a
Ze-qiang Qu et al.
PloS one, 7(1), e29641-e29641 (2012-01-12)
Previously we have demonstrated that a Rhodiola crenulata extract (RCE), containing a potent antioxidant salidroside, promotes neurogenesis in the hippocampus of depressive rats. The current study was designed to further investigate the protective effect of the RCE on neurogenesis in
Salidroside decrease expression of hypoxia-inducible factor-1α in cultured human lung cancer cells.
Li, B., et al.
African Journal of Pharmacy and Pharmacology, 34, 2526-2530 (2012)
Erin Wei Qian et al.
Journal of natural products, 75(4), 531-537 (2012-04-10)
Rhodiola rosea is a commonly used folk medicine for the treatment of high altitude sickness, mountain malhypoxia, and anoxia. Its active ingredient, salidroside [2-(4-hydroxyphenyl)ethyl β-D-glucopyranoside (1)], has been reported to have a broad spectrum of biological effects. However, the protective
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