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Merck

PHR1042

Prednisona

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

1,4-Pregnadieno-17α,21-diol-3,11,20-triona, 1- Cortisona, 17α,21-dihidroxi-1,4-pregnadieno-3,11,20-triona, Dehidrocortisona

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Fórmula empírica (notación de Hill):
C21H26O5
Número CAS:
Peso molecular:
358.43
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-160-3
Beilstein/REAXYS Number:
2065301
MDL number:
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Quality Segment

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1559006, traceable to Ph. Eur. P2900000

API family

prednisone

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

236-238 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1

InChI

1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key

XOFYZVNMUHMLCC-ZPOLXVRWSA-N

Gene Information

human ... NR3C1(2908)

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Prednisone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA8969 in the slot below. This is an example certificate only and may not be the lot that you receive.


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

STOT RE 2

Clase de almacenamiento

11 - Combustible Solids



Certificados de análisis (COA)

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