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PHR1535

Estrone

Name: Estrone
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Estrone, 1,3,5(10)-Estratrien-3-ol-17-one, 3-Hydroxy-1,3,5(10)-estratrien-17-one, Folliculin

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Fórmula empírica (notación de Hill):

C₁₈H₂₂O₂

Número CAS:

53-16-7

Peso molecular:

270.37

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823447

EC Number:

200-164-5

Beilstein/REAXYS Number:

1915077

MDL number:

MFCD00003620

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Propiedades

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1255001, traceable to Ph. Eur. E1700000

API family

estrone

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

258-260 °C (lit.)

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChI key

DNXHEGUUPJUMQT-CBZIJGRNSA-N

Gene Information

human ... ESR1(2099)

Descripción

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Estrone is a degradation product of the endogenous estrogen steroid, estradiol.

Application

Estrone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3933 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Pictogramas

GHS08

Palabra de advertencia

Danger

Códigos de peligro

H351,H360FD,H362

Indicaciones de precaución

P202 - P260 - P263 - P264 - P280 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)