T0254
L-Tryptophan
≥98% (HPLC)
Sinónimos:
(S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid
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Fórmula empírica (notación de Hill):
C11H12N2O2
Número CAS:
Peso molecular:
204.23
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-795-6
MDL number:
Beilstein/REAXYS Number:
86197
Servicio técnico
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Permítanos ayudarleNombre del producto
L-Tryptophan, reagent grade, ≥98% (HPLC)
grade
reagent grade
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
mp
280-285 °C (dec.) (lit.)
solubility
0.5 M HCl: 50 mg/mL
application(s)
cell analysis
SMILES string
N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChI key
QIVBCDIJIAJPQS-VIFPVBQESA-N
Gene Information
human ... TDO2(6999), TPH1(7166), TPH2(121278)
Application
L-tryptophan has been used for the isolation of bone marrow–derived neutrophils. It has also been used to identify the use of Raman microscopy as a tool to study the network of neurons in pathologically normal retina.
Biochem/physiol Actions
Tryptophan (Trp) is a heterocyclic, essential amino acid associated with growth, reproduction and immunity. Increased availability of tryptophan is necessary for the regulation of mood, cognition and behavior. The uptake of tryptophan by the brain depends on the plasma ratio of Trp to all of the other large neutral amino acids. Higher the ratio, greater is the Trp uptake.
Other Notes
Amino acid precursor of serotonin and melatonin
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Effects of tryptophan loading on human cognition, mood, and sleep.
Neuroscience and Biobehavioral Reviews, 34(3) (2010)
Tryptophan Catabolism Restricts IFN-??Expressing Neutrophils and Clostridium difficile Immunopathology
Mohamad El-Zaatari
Journal of Immunology (2014)
Raman microscopy of porcine inner retinal layers from the area centralis
J. Renwick
Molecular Vision (2007)