A1346
ASB-14
Sinónimos:
3-[N,N-Dimethyl(3-myristoylaminopropyl)ammonio]propanesulfonate, Amidosulfobetaine-14
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Fórmula empírica (notación de Hill):
C22H46N2O4S
Número CAS:
Peso molecular:
434.68
UNSPSC Code:
12161902
NACRES:
NA.28
MDL number:
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Permítanos ayudarleSMILES string
[S](=O)(=O)([O-])CCC[N+](CCCNC(=O)CCCCCCCCCCCCC)(C)C
InChI
1S/C22H46N2O4S/c1-4-5-6-7-8-9-10-11-12-13-14-17-22(25)23-18-15-19-24(2,3)20-16-21-29(26,27)28/h4-21H2,1-3H3,(H-,23,25,26,27,28)
InChI key
UTSXERRKRAEDOV-UHFFFAOYSA-N
description
zwitterionic
assay
≥95.0% (HPLC)
form
powder
mol wt
average mol wt >10,000
aggregation number
≥23
storage temp.
2-8°C
Quality Level
General description
ASB-14 comprises alkyl tails and amidosulfobetaine headgroup.
Application
ASB-14 has been used as a component of rehydration buffer for proteomic sample preparation from Leishmania donovani.
Zwitterionic detergent. Useful for solubilization of proteins, including membrane proteins, for 2D electrophoresis.
Biochem/physiol Actions
ASB-14 is useful in proteasome extraction especially for the membrane associated proteins. Along with CHAPS (3-(3-cholamidopropyl)dimethylammonio)-1-propanesulfonate), it is employed in protein solubilization even in the presence of thiourea.
Analysis Note
ASB-14 (amidosulfobetaine-14), a membrane solubilizing zwitterionic detergent (medium chain amidosulfobetaine surfactant), may be used in protein and macromolecule research for the preparative extraction and solubilization of proteins for separation and analysis by methods such as 2D-electrophoresis. ASB-14 may be used in tissue engineering for antigen removal (AR) for xenogeneic scaffold generation. ASB-14 may be used to develop and study zwitterionic micelles.
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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