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Merck

G2025

Glicerol

greener alternative

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for electrophoresis, ≥99% (GC)

Sinónimos:

1,2,3-Propanotriol, Glicerina

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About This Item

Fórmula lineal:
HOCH2CH(OH)CH2OH
Número CAS:
56-81-5
Peso molecular:
92.09
UNSPSC Code:
50161901
NACRES:
NA.21
PubChem Substance ID:
24895082
EC Number:
200-289-5
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722
assay:
≥99% (GC)
technique(s):
cell culture | insect: suitable
cell culture | mammalian: suitable
bp:
182 °C/20 mmHg (lit.)
vapor pressure:
<1 mmHg ( 20 °C)

Nombre del producto

Glicerol, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for electrophoresis, ≥99% (GC)

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

SMILES string

OCC(O)CO

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

BioReagent

assay

≥99% (GC)

form

viscous liquid

autoignition temp.

698 °F

greener alternative product characteristics

Safer Solvents and Auxiliaries
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

impurities

≤0.005% Chlorinated compounds
≤0.005% Sulfate (SO4)

refractive index

n20/D 1.474 (lit.)

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

density

1.25 g/mL (lit.)

suitability

suitable for electrophoresis

greener alternative category

Aligned

Quality Level

300

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Application

El glicerol se utiliza para la preparación de las muestras y la formación de geles para electroforesis en gel de poliacrilamida. El glicerol (5-10 %) aumenta la densidad de una muestra para que forme una capa en el fondo del pocillo de muestra de gel. El glicerol se utiliza también para ayudar a moldear los geles de gradiente y como estabilizador de proteínas y componente de tampones de almacenamiento.

Biochem/physiol Actions

El glicerol es de naturaleza higroscópica y es soluble en agua debido a sus tres grupos hidroxilo alcohólicos hidrófilos. Puede formar puentes de hidrógeno intermoleculares e intramoleculares, lo que lo convierte en una molécula muy flexible. El efecto fisiológico de la glicerina se debe a la inmunidad mediada por células, al aumento de la producción de IgG y al aumento de la liberación de histamina.
El glicerol se ha utilizado como:
  • suplemento durante el cultivo celular de Mycobacterium tuberculosis y Mycobacterium avium.
  • combustible durante el diseño de la pila de biocombustible enzimático.
  • matriz de compuesto líquido con 4-HCCA y 3-amino-quinolina para el análisis de glucanos neutros y ácidos.
  • matriz para SM con bombardeo rápido de átomos.
  • puede emplearse como matriz líquida en los estudios de cuantificación mediante análisis MALDI (espectrometría de masas con desorción/ionización mediante láser asistida por matriz).

General description

El glicerol es de naturaleza inodora, incolora y viscosa, y existe como un líquido con sabor dulce. Puede obtenerse naturalmente así como a partir de materia prima petroquímica. El glicerol tiene una amplia variedad de aplicaciones, y es una de las sustancias químicas más valiosas y versátiles de la naturaleza. Puede utilizarse como emoliente, disolvente, edulcorante, en formulaciones farmacéuticas, cosméticas, alimentarias y artículos de tocador. Es muy estable y puede almacenarse fácilmente a temperatura normal; también es no irritante y no tiene efectos adversos en el medio ambiente.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. Glycerol, with its high boiling point, low flammability, and polarity, is a standout choice. As a non-toxic and biodegradable compound, it aligns perfectly with the principles of ′Safer Solvents and Auxiliaries′ and ′Design for Degradation′. Click here for more information.

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
SHBT5045
SHBS3979
SHBR8854
SHBS2739
SHBR4187

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Is Product No. G2025 a sterile glycerol product?

    Our quality specifications for this product include cell culture testing, but the product is not sterile as it is shipped.

  6. What is the meaning of "Performance" in your specification sheet for Product No. G2025 (Glycerol)?

    The "Performance" test demonstrates that a cell freezing medium prepared using that product maintains the viability of mammalian cells after storing the cells for 5 to 7 days at -196 °C.

  7. What is the concentration of glycerol (e.g., Product No. G2025)?

    Based on a density of 1.261 g/mL for glycerol, and a molecular weight of 92.1 g/mol, the concentration of this liquid is 13.7 M.

  8. Can I autoclave glycerol (e.g., Product No. G2025) before using it (for example) for cell culture?

    Glycerol can be autoclaved for 20 minutes, as is or in a solution, generally at approximately 50%.

  9. In what solvent is glycerol (e.g., Product No. G2025) most soluble?

    Glycerol is miscible with water and alcohol at all concentrations. See: The chemicals encyclopedia published by the Royal Society of Chemistry, 12th ed., Entry# 4493.

  10. What is the viscosity of glycerol?

    The viscosity of glycerol is 648 Centistokes at 20 Deg C (68 Deg F).

  11. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Shelley L Forrest et al.
The Journal of comparative neurology, 522(17), 3900-3927 (2014-07-22)
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Benoît Ranchoux et al.
The American journal of pathology, 185(2), 356-371 (2014-12-17)
Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension (PH) characterized by progressive obstruction of small pulmonary veins and a dismal prognosis. Limited case series have reported a possible association between different chemotherapeutic agents and PVOD. We evaluated
Nazish Ahmed et al.
Tissue engineering. Part A, 20(15-16), 2224-2233 (2014-03-13)
One of the factors preventing clinical application of regenerative medicine to degenerative cartilage diseases is a suitable source of cells. Chondrocytes, the only cell type of cartilage, grown in vitro under culture conditions to expand cell numbers lose their phenotype
T W Chew et al.
Oncogene, 33(21), 2717-2727 (2013-07-03)
RAS and Rho small GTPases are key molecular switches that control cell dynamics, cell growth and tissue development through their distinct signaling pathways. Although much has been learnt about their individual functions in both cell and animal models, the physiological
Jian Ye et al.
PLoS pathogens, 11(10), e1005196-e1005196 (2015-10-03)
Aberrant viral RNAs produced in infected plant cells serve as templates for the synthesis of dsRNAs. The derived virus-related small interfering RNAs (siRNA) mediate cleavage of viral RNAs by post-transcriptional gene silencing (PTGS), thus blocking virus multiplication. Here, we identified
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Contenido relacionado

Product Information Sheet - G2025

Product Information Sheet

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