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Merck

N7381

βDinucleótido de β-nicotinamida y adenina hydrate

greener alternative

Grade AA-1

Sinónimos:

β-DPN, β-NAD, -NAD, Coenzima 1, Cozimasa, DPN, Nadide, Nucleótido de difosfopiridina

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Fórmula empírica (notación de Hill):
C21H27N7O14P2 · xH2O
Número CAS:
Peso molecular:
663.43 (anhydrous basis)
UNSPSC Code:
41106305
eCl@ss:
39200202
PubChem Substance ID:
NACRES:
NA.55
MDL number:
Biological source:
yeast
Form:
powder
Storage temp.:
−20°C
Servicio técnico
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biological source

yeast

Quality Level

type

Grade AA-1

form

powder

IVD

not for in vitro diagnostic use

greener alternative product characteristics

Waste Prevention
Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

color

white to off-white

greener alternative category

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI key

BAWFJGJZGIEFAR-NNYOXOHSSA-N

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.
β-Nicotinamide adenine dinucleotide (β-NAD) is a ubiquitous biomolecule containing an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.

Application

β-Nicotinamide adenine dinucleotide hydrate has been used as a supplement in chocolate agar plates for Haemophilus influenzae growth.

Biochem/physiol Actions

Aceptor de electrones
β-Nicotinamide adenine dinucleotide (β-NAD) is an electron carrier and a cofactor, significantly involved in enzyme-catalyzed oxido-reduction processes and many genetic processes. NAD cycles between the oxidized (NAD+) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth. NAD is also involved in microbial catabolism. β-NAD acts as a substrate for various enzymes in several cellular processes.

Packaging

Envasado por peso sólido.

Preparation Note

Produced by fermentation.

Other Notes

Esta es la forma común del NAD.


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

STOT SE 2

target_organs

Eyes,Central nervous system

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Iron-binding proteins in sputum of chronic bronchitis patients with Haemophilus influenzae infections
Vogel L, et al.
The European Respiratory Journal, 10(10), 2327-2333 (1997)
Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA-and EPAC1/Rac1-dependent actin cytoskeleton rearrangement
Umapathy NS, et al.
Journal of Cellular Physiology, 223(1), 215-223 (2010)
Experimental and theoretical electron density studies in large molecules: NAD+, beta-nicotinamide adenine dinucleotide
Guillot B, et al.
The Journal of Physical Chemistry B, 107(34), 9109-9121 (2003)