PHR1046
Éthylène glycol
Pharmaceutical Secondary Standard; Certified Reference Material
Synonyme(s) :
1,2-Éthanediol
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A propos de cet article
Formule linéaire :
HOCH2CH2OH
Numéro CAS:
Poids moléculaire :
62.07
NACRES:
NA.24
PubChem Substance ID:
eCl@ss:
39020501
UNSPSC Code:
41116107
EC Number:
203-473-3
MDL number:
Beilstein/REAXYS Number:
505945
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Laissez-nous vous aiderInChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1265515
vapor density
2.1 (vs air)
vapor pressure
0.08 mmHg ( 20 °C)
CofA
current certificate can be downloaded
autoignition temp.
752 °F
expl. lim.
15.3 %
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
Quality Level
SMILES string
OCCO
bp
195-198 °C
mp
−13 °C (lit.)
density
1.113 g/mL at 25 °C (lit.)
refractive index
n20/D 1.431 (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
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General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ethylene glycol can also be produced from fossil fuels (petroleum, natural gas and coal) and biomass-derived resources. It is a polyol having a wide range of industrial applications.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Ethylene glycol may be used as a standard in the determination of ethylene glycol present in serum samples using gas chromatography (GC).
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2089 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - STOT RE 2 Oral
target_organs
Kidney
Classe de stockage
10 - Combustible liquids
Certificats d'analyse (COA)
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Gas-chromatographic determination of ethylene glycol in serum
Porter H.W and Auansakul aA
Clinical Chemistry, 28, 75-78 (1982)
Yi Wang et al.
Journal of the American Chemical Society, 135(5), 1941-1951 (2013-01-16)
This article describes a robust method for the facile synthesis of small Ag nanocubes with edge lengths controlled in the range of 18-32 nm. The success of this new method relies on the substitution of ethylene glycol (EG)--the solvent most
Birgit Oberleitner et al.
Chemical communications (Cambridge, England), 49(16), 1615-1617 (2013-01-23)
This work describes an integrated approach for designing on demand Self-Assembled Monolayers (SAMs) on silicon oxides and particularly glass substrates for cell biology applications. Starting from commercially available compounds, the strategy relies on thiol-ene reaction and provides high quality SAMs
Laetitia Galea et al.
Biomaterials, 34(27), 6388-6401 (2013-06-13)
Calcium phosphates (CaPs) are widely used as bone graft substitutes but are inherently brittle, hence restricting their use to mechanically protected environments. Combining them with a tough polymer matrix could potentially lead to a composite with load-bearing properties. However, the
Liang Su et al.
Nature communications, 6, 6287-6287 (2015-02-18)
The enhancement of molecular absorption, emission and scattering processes by coupling to surface plasmon polaritons on metallic nanoparticles is a key issue in plasmonics for applications in (bio)chemical sensing, light harvesting and photocatalysis. Nevertheless, the point spread functions for single-molecule
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