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Merck

Y0000882

Adrenaline

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(−)-Epinephrine, (−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine

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A propos de cet article

Formule linéaire :
(HO)2C6H3CH(OH)CH2NHCH3
Numéro CAS:
51-43-4
Poids moléculaire :
183.20
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329831202
MDL number:
MFCD00002204
Beilstein/REAXYS Number:
2368277

Principaux documents

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InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

grade

pharmaceutical primary standard

API family

adrenaline

manufacturer/tradename

EDQM

mp

215 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

Catégories apparentées

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Adrenaline EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Adrenoceptor agonist.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

hcodes

H310

Hazard Classifications

Acute Tox. 2 Dermal

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Certificats d'analyse (COA)

Lot/Batch Number

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Jonathan D Jacobs et al.
Pediatrics, 133(1), e8-13 (2013-12-18)
Research suggests that hypertonic saline (HS) may improve mucous flow in infants with acute bronchiolitis. Data suggest a trend favoring reduced length of hospital stay and improved pulmonary scores with increasing concentration of nebulized solution to 3% and 5% saline
Michael B Levy et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(1), 58-63 (2013-12-18)
Avoidance strategies in patients with cow's milk allergy occasionally fail to protect these patients from inadvertent exposures, leading to life-threatening reactions. To assess the safety and efficacy of milk oral immunotherapy as an alternative therapeutic strategy. Patients (n = 280
Mark M Kushnir et al.
Clinical chemistry, 52(8), 1559-1567 (2006-06-17)
Congenital adrenal hyperplasia is a group of autosomal recessive disorders caused by a deficiency of 1 of 4 enzymes required for the synthesis of glucocorticoids, mineralocorticoids, and sex hormones. Analysis of 11-deoxycortisol (11DC), 17-hydroxyprogesterone (17OHP), 17-hydroxypregnenolone (17OHPr), and pregnenolone (Pr)
Phillip L Lieberman
The American journal of medicine, 127(1 Suppl), S6-11 (2014-01-05)
The International Classification of Diseases (ICD)-9 included a code only for anaphylactic shock. The improved ICD-10 coding defines the different symptoms and types of anaphylaxis and includes coding for anaphylaxis without shock. This new coding is consistent with the efforts
Giuseppe Luongo et al.
European journal of oral implantology, 7(2), 187-199 (2014-07-01)
The aim of this prospective multicentre study was to evaluate the clinical outcome of immediately loaded single implants. Patients were recruited at six clinical centres. Inclusion criteria were singletooth replacement in fully healed sites or post-extraction sockets with adequate bone
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