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Merck

1366002

USP

Lidocaine

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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A propos de cet article

Formule empirique (notation de Hill) :
C14H22N2O
Numéro CAS:
137-58-6
Poids moléculaire :
234.34
NACRES:
NA.24
PubChem Substance ID:
329750054
UNSPSC Code:
41116107
MDL number:
MFCD00026733

Principaux documents

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Nom du produit

Lidocaine, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

lidocaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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Catégories apparentées

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Lidocaine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay, identification and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Lidocaine
  • Lidocaine Hydrochloride Topical Solution
  • Lidocaine Hydrochloride Oral Topical Solution
  • Lidocaine Hydrochloride Jelly

Biochem/physiol Actions

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.
Na+ channel blocker; class IB antiarrhythmic.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Lidocaine
United States Pharmacopeia, 43(3), 2620-2620 (2020)
Lidocaine Hydrochloride Jelly
United States Pharmacopeia, 43(6), 2625-2625 (2020)
Corrine A Nief et al.
Cancers, 14(19) (2022-10-15)
Ethanol ablation is a minimally invasive, cost-effective method of destroying tumor tissue through an intratumoral injection of high concentrations of cytotoxic alcohol. Ethyl-cellulose ethanol (ECE) ablation, a modified version of ethanol ablation, contains the phase-changing polysaccharide ethyl-cellulose to reduce ethanol
Lidocaine Hydrochloride Oral Topical Solution
United States Pharmacopeia, 44(4), 2626-2626 (2020)
Yufei Zhang et al.
Journal of dairy science (2024-06-15)
High-yield dairy cows typically undergo intense cellular metabolism, leading to oxidative stress in their mammary tissues. Our study found that these high-yield cows had significantly elevated levels of hydrogen peroxide (H2O2), lipoperoxidase, and total antioxidant capacity in their blood, compared
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