Altered Intercellular Communication |
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Featured Solution: Small GTPase Activation Assays |
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The Small GTPase Activation Kits provide a quick and easy method for detecting active small GTPases. These assays isolate the active (GTP-bound) form of the protein with the binding domains of their downstream effectors immobilized on agarose beads. The isolated active GTPase is then detected by Western blot using a GTPase specific antibody. Complete kits include GTPase binding domain coupled to agarose beads, primary antibody, GDP, GTPγS, and buffer necessary to perform 20 or 30 pull-down assays. |
GTPase Binding Domain | Activation Assay | Catalog No. |
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Pak1 p21-binding domain (PAK1-PBD) | Rac1 Activation Assay Kit Rac1/Cdc42 Activation Assay Kit Rac2 Activation Assay Kit Cdc42 Activation Assay Kit |
17-283 17-441 17-369 17-286 |
Rhotekin Rho-binding domain (Rhotekin-RBD) | Rho Activation Assay Kit | 17-294 |
Raf1 Ras-binding domain (Raf1-RBD) | Ras Activation Assay Kit | 17-218 |
RalGDS Rap1-binding domain (RalGDS-RBP) | Rap1 Activation Assay Kit | 17-321 |
Ral binding protein 1 (RalPB1-RBD) | Ral Activation Assay Kit RalB Activation Assay |
17-300 17-439 |
Hallmarks of Aging |
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