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Merck

CXCR4

chemokine (C-X-C motif) receptor 4

Synonymes:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

neutralization
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
Espèces réactives
human
Application
ELISA
western blot
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
flow cytometry

immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-CXCR4 Antibody, clone 9B6G1, Rabbit Monoclonal, ,
Espèces réactives
human
Application
western blot
Anti-CXCR4 Antibody, clone 2L2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry

Proteins

Numéro du produit
Description
Espèce(s)
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CXCR4,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Cxcr4,
Espèce(s)
mouse