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Merck

D2050000

Diméthylsulfoxyde

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

DMSO, Sulfoxyde de méthyle

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A propos de cet article

Formule linéaire :
(CH3)2SO
Numéro CAS:
Poids moléculaire :
78.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
506008
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Nom du produit

Diméthylsulfoxyde, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

manufacturer/tradename

EDQM

availability

not available in (Sales restrictions may apply)

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Disclaimer

Refroidit facilement et revient doucement à la température de la pièce. Les produits solides peuvent être reliquéfiés par chauffage à la température ambiante sans abîmer le produit.

Application

Dimethyl sulfoxide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup


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A Hillarp et al.
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Apixaban is an oral direct factor Xa inhibitor developed for the prophylaxis and treatment of thromboembolic disorders. Laboratory monitoring is not necessary, but the effects on common coagulation reagents and assays constitute clinically valuable information. To investigate the effects of apixaban
Rory W Blackler et al.
British journal of pharmacology, 172(4), 992-1004 (2014-10-10)
Hydrogen sulphide is an important mediator of gastrointestinal mucosal defence. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is significantly limited by their toxicity in the gastrointestinal tract. Particularly concerning is the lack of effective preventative or curative treatments for NSAID-induced
S L Khaw et al.
Leukemia, 28(6), 1207-1215 (2014-01-10)
Overexpression of the prosurvival protein Bcl-2 marks many B-lymphoid malignancies and contributes to resistance to many commonly used chemotherapeutic agents. The first effective BH3 mimetic inhibitors of Bcl-2, ABT-737 and navitoclax, also target Bcl-xL, causing dose-limiting thrombocytopenia. This prompted the

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