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Merck

P4691

Protéine G-Agarose, Fast Flow (à débit élevé) from Streptococcus sp.

saline suspension

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A propos de cet article

UNSPSC Code:
41106500
MDL number:
Form:
saline suspension
Service technique
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form

saline suspension

extent of labeling

≥2 mg per mL

matrix

Highly cross-linked 4% beaded agarose, fast flow

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

≥20 mg/mL binding capacity (human IgG (I 4506))(in 20 mM sodium phosphate, pH 7.0)

storage temp.

2-8°C

Application

Protein G-agarose is used in affinity chromatography, protein chromatography, antibody purification and characterization, immunoaffinity matrices, protein A, G and L resins, and purification and detection. Protein G-agarose has been used to study breast cancer and falsely elevated thyroid-stimulating hormone (TSH).

Physical form

Suspension in 0.5 M NaCl containing 20% ethanol as a preservative

Preparation Note

Prepared with a genetically engineered Protein G which retains its high affinity for IgG and lacks albumin and Fab binding sites and membrane binding regions.


Classe de stockage

3 - Flammable liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Fan Jiang et al.
The Journal of pharmacology and experimental therapeutics, 324(1), 261-269 (2007-10-06)
Previously we have demonstrated that 3',4'-dihydroxyflavonol (DiOHF), a novel synthetic flavonol, protects against ischemia reperfusion injury in both heart and brain. In this study, we characterized the pharmacological effects of DiOHF on phagocytic and vascular NADPH oxidase. Superoxide release (lucigenin-enhanced
L Zahradova et al.
Neoplasma, 59(4), 440-449 (2012-04-12)
In a phase II clinical study, pretreated multiple myeloma patients with relapsing or stable disease received autologous anticancer vaccine containing dendritic cells loaded with Id-protein. Patients received a total of 6 vaccine doses intradermally in monthly intervals. No clinical responses were observed.
Bin Yi et al.
International journal of oncology, 38(6), 1565-1573 (2011-04-02)
CD176 (Thomsen-Friedenreich antigen) is a tumor-associated carbohydrate structure. In a previous study, we observed that the anti-CD176 antibody can induce the apoptosis of CD176-positive leukemic cells. In this study, we investigated the mechanisms of apoptosis induced by the CD176 antibody.