Learn more about the nextBioPharmDSP project: http://nextbiopharmdsp.eu
Golden LEAF Biomanufacturing Training and Education Center
850 Oval Drive, Raleigh, NC 27606
Different approaches for primary separation, capture and intermediate/ polishing steps will be evaluated for the ability to reduce the size and number of downstream unit operations and eliminate centrifugation.
Alternatives to batch processing for the capture step, such as continuous chromatography, will be evaluated to improve efficiency and reduce the need for expensive resins. Precipitation will also be evaluated as an approach to replace protein A chromatography as capture step.