Growing demand for high-quality plasmid DNA has increased the need for high productivity flexible manufacturing. Membrane chromatography provides an effective solution to alleviate the downstream bottleneck in plasmid purification.
This webinar will explore strategies for implementing an efficient and intensified plasmid removal process using anion exchange membrane chromatography. A comprehensive study evaluating the use of environmentally friendly detergents for enhanced endotoxin removal will be presented and the challenges faced by process developers will be addressed.
In this webinar, you will learn:
- Strategies to establish an efficient, intensified plasmid capture using convective anion exchange (AEX) chromatography.
- How this content is suitable for process development scientists and manufacturers
Speakers

André Kiesewetter
Merck
Senior Applications Engineer
André Kiesewetter is a senior applications engineer with more than twenty years of experience in Merck's downstream applications chromatography R&D team. In this role, he helps biopharmaceutical companies optimize, implement, and scale downstream technologies with a focus on developing best practices for the chromatographic purification of biomolecules. He has extensive expertise in bioprocessing operations and bioseparation technologies. André graduated from the University of Applied Sciences in Jena, Germany, with a degree in biotechnology engineering.

Oliver Prince, Ph.D.
Merck
Sr. Modality Expert for pDNA/mRNA, Process Solutions
Oliver Prince is the senior modality expert for pDNA/mRNA manufacturing within Merck. With more than a decade of experience as a scientist, he has also held roles in strategy and marketing servicing the life science community. In his current role, Oliver fosters innovation and growth through people engagement, identifying unmet needs, and monitoring trends in the pDNA/mRNA segment.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:Tue, September 9, 2025 4:00 PM CEST
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