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Merck

704105

Polycaprolactone

average Mn 45,000

Synonym(s):

2-Oxepanone homopolymer, 6-Caprolactone polymer

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About This Item

Linear Formula:
(C6H10O2)n
NACRES:
NA.21
UNSPSC Code:
12162002

Product Name

Polycaprolactone, average Mn 45,000

form

pellets

melt index

1.8 g/10 min (80 °C, 44 psi)

mol wt

Mn 40,000-50,000
Mw 48,000-90,000
average Mn 45,000

mp

56-64 °C
60 °C (lit.)

Quality Level

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Application

PCL can form a nanocomposite with graphene for the fabrication of biodegradable systems for bone tissue engineering.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

General description

Polycaprolactone (PCL) is a semi-crystalline linear resorbable aliphatic polyester that is composed of repeating units of hexanoate. It has good mechanical properties, miscibility, and biodegradability. PCL is a soft and hard-tissue compatible material that can be used in sutures and drug delivery systems.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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A novel degradable polycaprolactone networks for tissue engineering
Kweon H, et al.
Biomaterials, 24(5), 801-808 (2003)
Covalently linked biocompatible graphenepolycaprolactone composites for tissue engineering
Sayyar S, et al.
Carbon, 52(5), 296-304 (2013)
Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering
Williams JM, et al.
Biomaterials, 26(23), 4817-4827 (2005)
Synthesis of polycaprolactone: a review
Labet M and Thielemans W
Chemical Society Reviews, 38(12), 3484-3504 (2009)
Properties of thermoplastic blends: starch-polycaprolactone
Averous L, et al.
Polymer, 41(11), 4157-4167 (2000)

Articles

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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