biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GABRG2(2566)
Immunogen
Synthetic peptide from rat GABA-A receptor gamma 2 subunit from the N-terminus.
Application
Detect GABA A Receptor γ2 using this Anti-GABA A Receptor γ2 Antibody validated for use in ELISA, IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:500-1:1,000. Recognizes a 45-47 kDa protein.
Immunoprecipitation
ELISA
Optimal working dilutions must be determined by end user.
Immunoprecipitation
ELISA
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
GABA-A receptor gamma 2 subunit. No known cross reactivity with other gamma GABA-A receptor or alpha and beta subunits. The immunogen sequence is identical in human, mouse and bovine.
Physical form
Rabbit serum. Liquid.
Preparation Note
Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yi Pan et al.
Journal of neurochemistry, 94(2), 482-490 (2005-07-07)
The gamma-aminobutyric acid type C (GABA(C)) receptor is a ligand-gated chloride channel with distinct physiological and pharmacological properties. Although the exact subunit composition of native GABA(C) receptors has yet to be firmly established, there is general agreement that GABA rho
Qi Zhang et al.
Neural plasticity, 2018, 8919347-8919347 (2018-10-27)
Electroacupuncture (EA) has been reported to benefit hypertension, but the underlying mechanisms are still unclear. We hypothesized that EA attenuates hypertension, in part, through modulation of γ-aminobutyric acid (GABA) receptor function in the nucleus tractus solitarii (NTS). In the present
Bobae An et al.
eLife, 6 (2017-07-04)
There has been a longstanding debate on whether original fear memory is inhibited or erased after extinction. One possibility that reconciles this uncertainty is that the inhibition and erasure mechanisms are engaged in different phases (early or late) of extinction.
Fabio C Cruz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7437-7446 (2014-05-30)
Environmental contexts previously associated with drug use provoke relapse to drug use in humans and reinstatement of drug seeking in animal models of drug relapse. We examined whether context-induced reinstatement of cocaine seeking is mediated by activation of context-selected nucleus
Stephanie M Miller et al.
Brain structure & function, 223(2), 1025-1033 (2017-12-29)
The GABAA receptor provides the majority of inhibitory neurotransmission in the adult central nervous system but in immature brain is responsible for much of the excitatory drive, a requirement for normal brain development. It is well established that GABAA receptor
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