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Key Documents

AB5954

Sigma-Aldrich

Anti-GABA A Receptor γ2 Antibody

serum, Chemicon®

Synonym(s):

Anti-44600, Anti-CAE2, Anti-DEE74, Anti-ECA2, Anti-EIEE74, Anti-GEFSP3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GABRG2(2566)

Immunogen

Synthetic peptide from rat GABA-A receptor gamma 2 subunit from the N-terminus.

Application

Detect GABA A Receptor γ2 using this Anti-GABA A Receptor γ2 Antibody validated for use in ELISA, IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:500-1:1,000. Recognizes a 45-47 kDa protein.

Immunoprecipitation

ELISA

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

GABA-A receptor gamma 2 subunit. No known cross reactivity with other gamma GABA-A receptor or alpha and beta subunits. The immunogen sequence is identical in human, mouse and bovine.

Physical form

Rabbit serum. Liquid.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yi Pan et al.
Journal of neurochemistry, 94(2), 482-490 (2005-07-07)
The gamma-aminobutyric acid type C (GABA(C)) receptor is a ligand-gated chloride channel with distinct physiological and pharmacological properties. Although the exact subunit composition of native GABA(C) receptors has yet to be firmly established, there is general agreement that GABA rho
Qi Zhang et al.
Neural plasticity, 2018, 8919347-8919347 (2018-10-27)
Electroacupuncture (EA) has been reported to benefit hypertension, but the underlying mechanisms are still unclear. We hypothesized that EA attenuates hypertension, in part, through modulation of γ-aminobutyric acid (GABA) receptor function in the nucleus tractus solitarii (NTS). In the present
Fabio C Cruz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7437-7446 (2014-05-30)
Environmental contexts previously associated with drug use provoke relapse to drug use in humans and reinstatement of drug seeking in animal models of drug relapse. We examined whether context-induced reinstatement of cocaine seeking is mediated by activation of context-selected nucleus
Bobae An et al.
eLife, 6 (2017-07-04)
There has been a longstanding debate on whether original fear memory is inhibited or erased after extinction. One possibility that reconciles this uncertainty is that the inhibition and erasure mechanisms are engaged in different phases (early or late) of extinction.
Stephanie M Miller et al.
Brain structure & function, 223(2), 1025-1033 (2017-12-29)
The GABAA receptor provides the majority of inhibitory neurotransmission in the adult central nervous system but in immature brain is responsible for much of the excitatory drive, a requirement for normal brain development. It is well established that GABAA receptor

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